How Do You Spell GUANASE?

Pronunciation: [ɡwˈɑːne͡ɪs] (IPA)

Guanase is a word often used in the medical field to refer to an enzyme that helps break down guanine, a building block of DNA and RNA. The spelling of Guanase follows the International Phonetic Alphabet (IPA) phonetic transcription, with the "g" pronounced as /ɡwɑnəseɪ/. This phonetic transcription represents the unique combination of a hard "g" and a "w" sound at the beginning, followed by the vowel "a" and the suffix "ase." Proper spelling and pronunciation of Guanase are essential in the medical industry to avoid confusion and ensure effective communication.

GUANASE Meaning and Definition

1. Guanase is an enzyme that is primarily found in the liver and kidneys of mammals, including humans. It is also present in certain bacteria and fungi. The function of guanase is to catalyze the hydrolysis of guanine, a nitrogenous base found in nucleic acids like DNA and RNA. By breaking down guanine, guanase helps in the recycling of this component and the regulation of the nucleotide pool within cells.

   Guanase is classified as a hydrolase, as it aids in the cleavage of a chemical bond using water molecules. More specifically, guanase cleaves the guanine molecule at the C-N bond, leading to the formation of xanthine and ammonia as byproducts. The generated xanthine can be further metabolized to uric acid, which is then excreted from the body.

   The activity of guanase is crucial for maintaining optimal levels of guanine and other nucleotides involved in various cellular processes. Dysfunction or deficiency of guanase can have significant implications on the metabolism of nucleic acids, leading to disorders such as Lesch-Nyhan Syndrome, an inherited condition characterized by high levels of uric acid in the body.

   In addition to its role in nucleotide metabolism, guanase has been studied for its potential applications in cancer treatment. Its ability to selectively target and degrade guanine derivatives in cancer cells has shown promising results as a therapeutic approach. Further research is underway to explore the full potential of guanase in medicine and biotechnology.

Common Misspellings for GUANASE

• Gua.ase
• Guafase
• Gualase
• Guaoase
• Guanise
• Guancse
• Guana3e
• Guanace
• Guanaqe
• Guanare
• Guanasu
• Guanasm
• Guanasa
• Guanasg
• g uanase
• gu anase
• gua nase
• guan ase
• guana se
• guanas e

Etymology of GUANASE

The word "Guanase" derives from the term "guanine deaminase". The word "guanine" comes from the Spanish word "guano", meaning "dung" or "manure", which was used to refer to deposits of bird or bat excrement that contain guanine. The suffix "-ase" is commonly used in biochemistry to denote an enzyme. Therefore, "guanase" refers to an enzyme that catalyzes the deamination of guanine, a nitrogenous base found in DNA and RNA.

Plural form of GUANASE is GUANASES