GRF NH Meaning and
Definition
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GRF NH stands for Growth Hormone Receptor Knockout Nuclear Hypothalamus, which refers to a genetically modified animal model used in scientific research. The term can be broken down into its component parts for a better understanding.
Growth Hormone (GH) is a peptide hormone produced and secreted by the pituitary gland. It plays a crucial role in stimulating growth, development, and metabolism in humans and other animals. GH acts by binding to a specific receptor located on the cell surface, known as the Growth Hormone Receptor (GHR).
Knockout indicates a genetic modification technique wherein a specific gene is deliberately disabled or "knocked out" in an organism. In this case, the gene responsible for encoding the GHR is deliberately deactivated or removed from the organism's genome.
Nuclear Hypothalamus refers to the hypothalamus region of the brain, which has important regulatory functions, including the control of growth hormone secretion.
Therefore, GRF NH refers to an animal model in which the growth hormone receptor gene has been knocked out specifically in the nucleus of the hypothalamus. This genetic modification results in the absence or dysfunction of growth hormone receptors in the hypothalamus, which can be useful for studying the effects of this particular alteration on growth, development, metabolism, and related physiological processes in organisms. This model enables researchers to investigate the specific role of growth hormone in the hypothalamus and its impact on various biological functions.
Common Misspellings for GRF NH
- frf nh
- vrf nh
- brf nh
- hrf nh
- yrf nh
- trf nh
- gef nh
- gdf nh
- gff nh
- gtf nh
- g5f nh
- g4f nh
- grd nh
- grc nh
- grv nh
- grg nh
- grt nh
- grr nh
- grf bh
- grf mh
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