GRANULOCYTIC SARCOMA Meaning and
Definition
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Granulocytic sarcoma, also known as myeloid sarcoma or chloroma, is a rare solid tumor composed of immature myeloid cells. It is a localized extramedullary manifestation of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Granulocytic sarcoma typically arises in bone, soft tissue, lymph nodes, or skin, but it can occur in any organ or tissue.
The term "granulocytic" refers to the type of cells involved in the tumor, which are usually myeloblasts, promyelocytes, or immature granulocytes. These cells are part of the granulocytic lineage in the bone marrow and are responsible for fighting infection. However, in granulocytic sarcoma, these cells accumulate outside of the bone marrow, forming a mass or tumor.
Granulocytic sarcoma is often seen in patients with a history of AML or MDS, sometimes occurring before or concurrently with the hematologic disease. However, it can also present as an isolated manifestation without found in the bone marrow or blood. The exact cause of granulocytic sarcoma is not well understood, but it is believed to be related to genetic abnormalities and dysregulation of the myeloid cell lineage.
Clinically, granulocytic sarcoma is characterized by localized swelling, pain, and inflammation in the affected area. Diagnosis is typically confirmed through biopsy and immunohistochemistry, which can identify the presence of myeloid markers. Treatment often involves a combination of surgery, radiation therapy, and chemotherapy, tailored according to the underlying hematologic disorder. Granulocytic sarcoma is generally associated with a poor prognosis due to its aggressive nature and high risk of rel
Common Misspellings for GRANULOCYTIC SARCOMA
- franulocytic sarcoma
- vranulocytic sarcoma
- branulocytic sarcoma
- hranulocytic sarcoma
- yranulocytic sarcoma
- tranulocytic sarcoma
- geanulocytic sarcoma
- gdanulocytic sarcoma
- gfanulocytic sarcoma
- gtanulocytic sarcoma
- g5anulocytic sarcoma
- g4anulocytic sarcoma
- grznulocytic sarcoma
- grsnulocytic sarcoma
- grwnulocytic sarcoma
- grqnulocytic sarcoma
- grabulocytic sarcoma
- gramulocytic sarcoma
- grajulocytic sarcoma
- grahulocytic sarcoma
Etymology of GRANULOCYTIC SARCOMA
The term "Granulocytic Sarcoma" is a medical term used to describe a rare form of cancer, also known as extramedullary myeloid sarcoma. It originates from two constituents:
1. Granulocytic: This is derived from the word "granulocyte", which refers to a type of white blood cells called granulocytes. These cells are a crucial part of the immune system and aid in fighting infection.
2. Sarcoma: This term comes from the Greek word "sarkos", meaning "flesh". Sarcoma is a general medical term used to describe malignant tumors that arise from connective tissues, such as bones, muscles, cartilage, or blood vessels.
Therefore, "Granulocytic Sarcoma" combines these elements to describe a tumor that arises from granulocytic cells.
