The word "GPUHF" is an abbreviation for "Great Pyrenees Up High Five". It is spelled as /dʒiː.piː.juː.eɪtʃ.ef/, with each letter representing a sound in the word. The first two letters, "GP", represent the sound /dʒiː/, followed by the sound /piː/ for the "P". The letter "U" is pronounced as /juː/, and the next two letters, "H" and "F", represent the sounds /eɪtʃ/ and /ef/ respectively.