The Gomori procedure is a diagnostic test utilized in pathology to identify the presence of specific enzymes within tissue or cells. The spelling of the word "Gomori" is pronounced as /ɡoʊˈmɔri/ using the International Phonetic Alphabet transcription. The first syllable is pronounced as "go," with the "o" being a long vowel sound. The second syllable is pronounced as "more" with the stress on the "mor" and an "i" at the end pronounced as "ee." The spelling accurately represents the pronunciation of the name of the procedure's creator, George Gomori.
The Gomori procedure is a histological staining technique used in the field of pathology to visualize and identify specific cellular structures or substances. It is primarily employed to detect the presence of acid phosphatase enzymes in tissues. The procedure was named after George Gomori, the Hungarian-American pathologist who developed this staining method.
The Gomori procedure involves treating tissue sections with a specialized staining solution known as Gomori's method. This solution consists of a combination of potassium hexacyanoferrate, sodium sulfate, and lead nitrate. This stain selectively reacts with acid phosphatase enzymes, resulting in a visible blue-black coloration.
By utilizing the Gomori procedure, pathologists can identify acid phosphatase activity in various cell types or tissues, aiding in the diagnosis and understanding of specific diseases or pathological conditions. Acid phosphatase enzymes play a crucial role in many cellular processes, and their abnormal or excessive activity can be indicative of certain diseases such as prostate cancer, Gaucher's disease, or lysosomal storage disorders.
The Gomori procedure has proven to be a reliable and widely used technique in the field of pathology due to its ability to highlight acid phosphatase activity and provide vital information for diagnostic purposes. It is often employed alongside other staining methods to obtain a comprehensive analysis of cellular structures and functions.
The word "Gomori procedure" is named after a Hungarian-American pathologist named George Gomori. He developed a method called the "Gomori staining procedure" for visualizing certain substances, such as reticulin fibers, mitochondria, and muscle cells, in biological tissues. Gomori's contributions in staining techniques and histochemistry have had a lasting impact on the field of pathology.