Goldarine, also known as GW501516, is a selective androgen receptor modulator (SARM) that functions as a performance-enhancing drug. It was originally developed in the early 2000s for its potential application in treating metabolic disorders such as obesity, diabetes, and dyslipidemia. However, due to its ability to improve endurance and athletic performance, it gained popularity as a supplement among bodybuilders and athletes.
Goldarine works by activating the peroxisome proliferator-activated receptor delta (PPARδ), which plays a crucial role in various metabolic processes. Activation of PPARδ leads to an increase in the expression of genes involved in fatty acid oxidation, thus promoting the utilization of fats for energy production. This mechanism enhances endurance, as it allows the body to tap into its fat reserves for a sustained energy supply.
Although Goldarine is not officially approved for human use, it is widely available in the form of research chemicals and supplements. Users claim that it can enhance stamina, improve muscle definition, and aid in fat loss, making it attractive to individuals seeking to optimize their physical performance.
It is important to note that the use of Goldarine is controversial, as its long-term effects and potential health risks are not well-studied. Some concerns revolve around its potential association with cancer development, as studies on mice showed tumor growth at high doses. Therefore, caution should be exercised when considering Goldarine supplementation, and it is recommended to consult with a healthcare professional before using this compound.
