GLIOBLASTOMA MULTIFORME Meaning and
Definition
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Glioblastoma multiforme (GBM) is a highly aggressive and malignant brain tumor that originates in the brain's supportive tissue, called glial cells. It is the most common and deadliest type of glioma, accounting for approximately 15% of all primary brain tumors. GBM can occur in any part of the brain, but most commonly arises in the cerebral hemispheres.
This tumor is characterized by its infiltrative nature, meaning it invades surrounding healthy brain tissue, making complete surgical removal nearly impossible. It is also known for its rapid growth and ability to form abnormal blood vessels, leading to increased tumor size and pressure on adjacent brain structures.
Symptoms of glioblastoma multiforme vary depending on the location of the tumor but commonly include progressive neurological deficits such as severe headaches, seizures, cognitive impairment, personality changes, and focal weakness or numbness.
Prognosis for glioblastoma multiforme is generally poor, with a median survival time of about 15 months, even with aggressive treatment. Treatment options typically include surgical resection, if feasible, followed by radiation therapy and chemotherapy. However, due to the infiltrative nature of the tumor, uncontrolled cell division, and development of resistance to treatment, GBM often recurs and may become resistant to further therapy.
Overall, glioblastoma multiforme is a highly malignant brain tumor originating from glial cells, presenting with infiltrative growth, rapid expansion, and aggressive behavior. It poses significant challenges for effective treatment and carries a generally poor prognosis.
Common Misspellings for GLIOBLASTOMA MULTIFORME
- flioblastoma multiforme
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Etymology of GLIOBLASTOMA MULTIFORME
The word "Glioblastoma Multiforme" has a Greek and Latin etymology. Here is the breakdown:
1. Glioblastoma:
- "Glio" comes from the Greek word "gliā" (γλία), meaning "glue". It refers to the glial cells, which are non-neuronal cells that provide support and protection to the neurons in the central nervous system (brain and spinal cord).
- "Blastoma" comes from the Greek word "blastos" (βλαστός), meaning "embryo" or "bud". In medical terminology, "blastoma" is a suffix that indicates a tumor originating from embryonic or immature cells.
So, "glioblastoma" essentially means a tumor that arises from the glial cells in the brain or spinal cord.
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