Giant papillary conjunctivitis (GPC) is a medical condition characterized by inflammation and irritation of the conjunctiva, which is the thin and transparent membrane that covers the white part of the eyes and lines the inner surface of the eyelids. It is referred to as "giant" papillary conjunctivitis due to the presence of large, raised bumps, also known as papillae, on the inner surface of the upper eyelid, which are a defining feature of the condition.
GPC is commonly associated with the prolonged use of contact lenses, usually soft lenses, and it is considered to be an allergic reaction to the presence of foreign materials, such as proteins from tear film deposits, trapped under the lenses. Symptoms of GPC may include redness, itching, foreign body sensation in the eyes, excessive tearing, mucus discharge, and discomfort upon wearing contact lenses.
If left untreated, GPC can lead to complications like corneal abrasions and ulcers, which may impair vision. Treatment usually involves avoiding contact lens wear until symptoms subside, proper cleaning and disinfection of lenses, using lubricating eye drops or artificial tears to soothe irritation, and in severe cases, prescription medications such as corticosteroids or mast cell stabilizers may be required.
Regular check-ups with an eye care professional are recommended for individuals with GPC, as proper eye care and lens hygiene can help prevent and manage the condition effectively.
