GGT is an abbreviation for gamma-glutamyltransferase, which refers to an enzyme found in various tissues in the body. It is primarily present in the liver, but also in the kidneys, pancreas, and intestines. GGT plays a significant role in the metabolism of glutathione, a major antioxidant in the body.
From a medical standpoint, GGT is commonly used as a diagnostic marker to assess liver health and to detect liver-related disorders. Elevated GGT levels in the blood are indicative of liver dysfunction or damage. Conditions such as liver inflammation (hepatitis), liver cirrhosis, alcoholic liver disease, bile duct obstruction, and certain drug toxicities can result in increased GGT levels. Therefore, GGT is often included in liver function tests to aid in the diagnosis and monitoring of liver diseases.
Additionally, GGT levels can be affected by alcohol consumption, making it an important indicator for alcohol-related liver disorders. Since GGT is highly concentrated in the liver, its levels tend to rise in response to alcohol abuse or chronic alcohol intake. Tracking GGT levels can also help assess an individual's response to alcohol detoxification or abstinence programs.
In summary, GGT is an enzyme that plays a crucial role in the metabolism of glutathione and serves as a diagnostic marker for liver diseases, including alcohol-related disorders. Monitoring GGT levels helps medical professionals assess liver health and provides important insights into the functioning and integrity of the liver.
