GERM LINE GENE THERAPY Meaning and
Definition
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Germ line gene therapy is a specialized branch of genetic engineering that aims to modify the DNA of germ cells, the cells that give rise to eggs and sperm, in order to introduce heritable genetic changes. It involves the deliberate alteration of genes in germ cells to prevent the transmission of inheritable diseases or to enhance certain desired traits to future generations.
Unlike somatic gene therapy, which targets non-reproductive cells and only affects the individual being treated, germ line gene therapy targets the reproductive cells, which means that any modifications made will be passed on to subsequent generations. This raises ethical and safety concerns, as the implications of altering the genetic makeup of future generations are uncertain and potentially far-reaching.
Germ line gene therapy holds great promise for the prevention or treatment of genetic disorders that are inherited in a predictable pattern. By correcting or replacing faulty genes in germ cells, it could potentially eliminate or significantly reduce the risk of passing on genetic diseases to offspring.
However, germ line gene therapy also carries significant ethical considerations and potential risks. There are concerns about unintended consequences and the potential for unintended genetic changes. Furthermore, the introduction of inheritable genetic modifications raises questions about the boundaries of genetic engineering, as it has implications not just for individuals, but for future generations as well. Therefore, careful consideration of the ethical, legal, and social implications is necessary before germ line gene therapy can be pursued.
Common Misspellings for GERM LINE GENE THERAPY
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