GENE TRANSLOCATION Meaning and
Definition
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Gene translocation refers to a type of genetic rearrangement where a segment of DNA is transferred from its original position on one chromosome to a different location on another chromosome. This process can occur spontaneously or be induced by external factors such as radiation exposure or certain chemicals. Gene translocation can lead to significant changes in the genetic makeup of an organism.
During gene translocation, a segment of DNA breaks off from one chromosome and attaches itself to a different chromosome. This can result in the fusion of two separate genes, disruption of existing genes, or creation of entirely new gene sequences. As a consequence, the normal functioning of genes may be altered, which can have profound effects on the phenotype or physical characteristics of an organism.
Gene translocation can cause various genetic disorders and cancers. In some cases, it can also lead to chromosomal disorders like Down syndrome and chronic myelogenous leukemia. While some translocations may have no apparent effect on an individual's health, others can be detrimental and have significant implications.
The study of gene translocation is of particular interest in genetic research, as it helps scientists understand the complex mechanisms behind genetic diseases and can potentially provide insights into new therapeutic approaches. Techniques such as fluorescence in situ hybridization (FISH) and molecular cytogenetics are commonly used to detect and analyze gene translocations in both research and clinical settings.
Common Misspellings for GENE TRANSLOCATION
- fene translocation
- vene translocation
- bene translocation
- hene translocation
- yene translocation
- tene translocation
- gwne translocation
- gsne translocation
- gdne translocation
- grne translocation
- g4ne translocation
- g3ne translocation
- gebe translocation
- geme translocation
- geje translocation
- gehe translocation
- genw translocation
- gens translocation
- gend translocation
- genr translocation
Etymology of GENE TRANSLOCATION
The etymology of the word "gene translocation" can be broken down as follows:
1. Gene: The term "gene" traces its origins to the German word "Gen" coined by Wilhelm Johannsen in 1909. It was derived from the Greek word "genos" meaning "birth, origin, or race" and was introduced to describe the basic unit of heredity.
2. Translocation: The term "translocation" comes from the Latin word "translocare", which comprises two components: "trans" meaning "across" or "beyond", and "locare" meaning "to place or put". Translocation, in its broad sense, refers to the act of moving something from one place to another.
Therefore, when combined, the term "gene translocation" refers to the movement or relocation of a gene from its original position to a different location within the genome.
