GELSOLIN Meaning and
Definition
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Gelsolin is a protein that plays a crucial role in regulating the structure and dynamics of the cytoskeleton in eukaryotic cells. It acts as an actin filament severing and capping protein, which means it can cut actin filaments into smaller fragments and also bind to the ends of actin filaments to inhibit further polymerization. In this way, gelsolin can control the length and stability of actin filaments, which are vital for cell shape, movement, and various cellular processes.
Gelsolin is widely distributed throughout different tissues and cell types, and its expression levels can vary depending on specific physiological conditions and developmental stages. It is involved in a range of cellular activities, including cell migration, membrane remodeling, cytokinesis, and phagocytosis.
Furthermore, gelsolin has been implicated in several disease conditions and disorders. Mutations in the gene encoding gelsolin have been associated with various forms of familial amyloidosis, a group of inherited diseases characterized by the deposition of amyloid protein fibers in different organs and tissues. Altered gelsolin function has also been observed in other pathological conditions such as cancer, cardiovascular diseases, and neurodegenerative disorders.
In summary, gelsolin is a multifunctional protein that modulates the organization and dynamics of actin filaments, influencing critical cellular processes. Its role extends beyond normal cell function, as it has been linked to various diseases, making it a subject of interest in both basic research and clinical studies.
Common Misspellings for GELSOLIN
- felsolin
- velsolin
- belsolin
- helsolin
- yelsolin
- telsolin
- gwlsolin
- gslsolin
- gdlsolin
- grlsolin
- g4lsolin
- g3lsolin
- geksolin
- gepsolin
- geosolin
- gelaolin
- gelzolin
- gelxolin
- geldolin
- geleolin
Etymology of GELSOLIN
The word "gelsolin" is derived from the combination of two terms: "gel" and "sol".
The term "gel" comes from the late 19th-century physical chemistry and colloidal science, which referred to a semisolid, jelly-like substance forming when a dispersion medium (such as a liquid) is infiltrated by a dispersion phase (such as a solid). The word "gel" is believed to originate from the English word "goo", which is an onomatopoeic term imitating a viscous, sticky substance.
The term "sol" comes from the Latin word "solventem", meaning "loosening" or "dissolving". In colloidal science, a "sol" refers to a solid dispersed in a liquid, resulting in a stable suspension.
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