GANGLIOCYTIC PARAGANGLIOMA Meaning and
Definition
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Gangliocytic paraganglioma is a rare, benign tumor that typically originates in the digestive system, most commonly found in the duodenum - the first part of the small intestine. This tumor is classified as a neuroendocrine neoplasm, meaning it arises from cells that have both neural and endocrine characteristics.
The term "gangliocytic" refers to the presence of ganglion-like cells, which are cells that resemble neurons and are characteristic of this tumor. These ganglion cells are often found in close association with paraganglioma-like cells, which are endocrine cells that produce specific hormones.
Gangliocytic paraganglioma typically presents as a slow-growing mass that can cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting, and gastrointestinal bleeding. It is more commonly diagnosed in adults, with a slight male preponderance.
Macroscopically, gangliocytic paraganglioma appears as a well-defined, yellowish or reddish firm mass. Microscopically, it is characterized by the presence of ganglion-like cells, paraganglioma-like cells, and spindle-shaped sustentacular cells which surround and support the tumor cells.
Although gangliocytic paraganglioma is predominantly benign, it can occasionally exhibit aggressive behavior with local invasion or metastasis. Therefore, complete surgical resection is the primary treatment. Prognosis is generally excellent, but long-term follow-up is recommended due to the potential for recurrence or metastasis.
Given the rarity and unique histological features of this tumor, accurate diagnosis and proper management require expert evaluation by a multidisciplinary team consisting of gastroenterologists, pathologists, and oncologists.
Common Misspellings for GANGLIOCYTIC PARAGANGLIOMA
- fangliocytic paraganglioma
- vangliocytic paraganglioma
- bangliocytic paraganglioma
- hangliocytic paraganglioma
- yangliocytic paraganglioma
- tangliocytic paraganglioma
- gzngliocytic paraganglioma
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- gajgliocytic paraganglioma
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- ganvliocytic paraganglioma
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- ganhliocytic paraganglioma
- ganyliocytic paraganglioma
- gantliocytic paraganglioma
Etymology of GANGLIOCYTIC PARAGANGLIOMA
The word "Gangliocytic Paraganglioma" is formed by the combination of three terms: "gangliocytic", "paraganglioma", and "ganglioma". Here is the etymology of each term:
1. Gangliocytic:
- "Ganglio-" originates from the Greek word "ganglion", which means "knot" or "swelling". In medical terminology, it refers to a mass or a cluster of nerve cells.
- "-Cytic" is derived from the Greek word "kutos", meaning "cell". It is commonly used as a suffix in medical terms to indicate "pertaining to cells".
2. Paraganglioma:
- "Para-" comes from the Greek word "para", meaning "beside" or "near". In medical terminology, it often indicates "adjacent" or "alongside".
