Fusobacterium necrophorum is a type of bacteria commonly found in the human mouth and throat. The word "Fusobacterium" is pronounced [fjuːzoʊbæktɪriəm], with emphasis on the first syllable. "Necrophorum" is pronounced [nɛkrəfoʊrəm], with emphasis on the second syllable. The spelling of the word "Fusobacterium necrophorum" is based on the Latin roots "fusus" (spindle) and "necro-" (dead), referring to its rod-shaped appearance and ability to cause tissue death. This bacterial species can cause various infections, including Lemierre's syndrome, which can be life-threatening.
Fusobacterium necrophorum is a Gram-negative, anaerobic, rod-shaped bacterium belonging to the Fusobacterium genus. It is often found inhabiting the oral cavity and gastrointestinal tract of both humans and animals.
This bacterium is considered an opportunistic pathogen, causing various infections in humans. It has been associated with Lemierre's syndrome, a rare but severe condition characterized by thrombophlebitis of the internal jugular vein, necrotic tonsillitis, and distant organ infections such as septicemia or pneumonia. It is also known to be a causative agent of other infections, including peritonsillar abscesses, sinusitis, and pleuropulmonary infections.
Fusobacterium necrophorum possesses several virulence factors that contribute to its pathogenicity. These include the production of various enzymes, toxins, and adhesins that allow the bacterium to adhere to and invade host tissues. Its ability to form aggregates called biofilms on host surfaces enhances its survival and resistance to antibiotics.
Diagnosing infections caused by Fusobacterium necrophorum typically involves obtaining a clinical sample and subjecting it to microbiological culture and identification techniques. Antibiotic susceptibility testing is crucial to guide appropriate treatment since this bacterium has shown resistance to certain antimicrobial agents.
Treatment usually involves the administration of antibiotics, such as penicillin or metronidazole, that are effective against anaerobic bacteria. In some severe cases, surgical intervention may be necessary to drain abscesses or remove infected tissues. Early diagnosis and prompt treatment are crucial in mitigating the potentially life-threatening complications associated with infections caused by Fusobacterium necrophorum.
The word "Fusobacterium" is derived from the Latin term "fusus" meaning "spindle", and "bacterium", which comes from the Greek word "baktērion" meaning "small stick". "Necrophorum" is derived from the Greek term "nekros", meaning "dead", and the Latin term "forum", meaning "marketplace" or "gathering place".
Therefore, "Fusobacterium necrophorum" can be translated as "spindle-shaped bacteria associated with dead tissue".