FEULGEN REACTION Meaning and
Definition
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The Feulgen reaction is a histochemical staining technique used in the field of cytology and histology to specifically identify and visualize DNA within cells or tissues. It was discovered by the German chemist Robert Feulgen in the 1920s. The reaction is based on the principle that DNA, the genetic material of cells, can be selectively stained with a specific dye called Feulgen stain.
In the Feulgen reaction, cells or tissue sections are first treated with a strong acid, which breaks down the DNA into individual nucleotides. These nucleotides then react with the Feulgen stain, resulting in the formation of a colored complex. The stained DNA is usually observed under a microscope as dark purple, brown, or red dots or bands.
The Feulgen reaction is particularly useful for studying the amount of DNA in cells, as it allows researchers to measure DNA content and determine various aspects related to cell proliferation, such as DNA synthesis, cell cycle phases, and ploidy. Furthermore, it can be employed to identify and differentiate different types of cells based on their DNA staining patterns, aiding in the diagnosis of various pathological conditions, genetic abnormalities, and cancer research.
In summary, the Feulgen reaction is a histochemical technique that enables the visualization and quantification of DNA within cells or tissues, providing valuable information for understanding cellular processes and aiding in the field of medicine and biology.
Common Misspellings for FEULGEN REACTION
- deulgen reaction
- ceulgen reaction
- veulgen reaction
- geulgen reaction
- teulgen reaction
- reulgen reaction
- fwulgen reaction
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Etymology of FEULGEN REACTION
The word Feulgen reaction is named after Friedrich Feulgen, a German biochemist and cytologist. Friedrich Feulgen developed a staining technique in the early 20th century to identify DNA in cells, which later became known as the Feulgen reaction or Feulgen stain.
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