Pronunciation: [fˈɛɹɐtˌɪn] (IPA) 
The spelling of the word "ferratin" can be explained using the IPA phonetic transcription. The first syllable "fer" is pronounced as /fɛr/, with the "e" sound similar to the "e" in "men". The second syllable "ra" is pronounced as /ræ/, with the "a" sound similar to the "a" in "cat". The final syllable "tin" is pronounced as /tɪn/, with the "i" sound similar to the "i" in "bin". Overall, the word is pronounced as /fɛrætɪn/.
Ferratin is a substance that plays a crucial role in iron storage and transport within the body. It is a protein complex composed of ferritin subunits, which bind and store iron in a soluble, non-toxic form. The protein is primarily found within cells, particularly in the liver, spleen, and bone marrow.
The primary function of ferratin is to maintain iron homeostasis by regulating iron levels within the body. It carries out this function by effectively buffering iron concentrations, preventing the excess accumulation of iron that could be harmful to cells and tissues. Ferratin acts as a reservoir for iron, releasing it when needed and sequestering it when iron levels are high.
The structure of ferratin allows it to store thousands of iron atoms in its core. These iron atoms are sequestered and shielded from direct contact with cells, which helps to prevent oxidative damage that can occur from excess iron. In addition to its role in iron storage, ferratin also plays a role in iron transport, releasing iron in a controlled manner to cells and tissues that require it.
Ferratin levels in the blood can be measured to assess iron stores within the body. Low levels of ferratin are associated with iron deficiency anemia, while elevated levels can indicate iron overload disorders such as hemochromatosis.
In summary, ferratin is a protein complex involved in iron storage and transport, helping to maintain iron homeostasis within the body and preventing iron toxicity.
1. An organic iron compound stored in the tissues of the body. 2. An artificially prepared albuminate of iron said to be identical with the iron of the tissues; a reddish brown powder; recommended especially in acute anemia in doses of gr. 5-10 (0.3-0.6).
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
