FEEDER CELL Meaning and
Definition
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A feeder cell refers to a specialized type of cell that is used to support the growth, proliferation, and maintenance of other cells in a laboratory or research setting. Specifically, feeder cells are often utilized in the cultivation of stem cells and other types of cells that are difficult to grow and maintain outside their natural environment or in isolation.
Feeder cells play a vital role in cell culture by providing a substrate or surface onto which the target cells can attach and grow. These feeder cells are typically from a different type or species than the cells being cultured, and they are carefully selected to provide optimum conditions for growth. The feeder cells are often irradiated or treated to prevent them from multiplying and overgrowing the target cells.
The exact type or source of feeder cells can vary depending on the specific cell type being cultured, but examples include mouse embryonic fibroblasts and certain types of cells derived from animals, such as fibroblasts, epithelial cells, or glial cells. These feeder cells release various growth factors, signaling molecules, and extracellular matrix components that support the survival, proliferation, and differentiation of the cells being grown.
Feeder cells are an integral component of cell culture techniques and are important tools in various research areas, including stem cell research, tissue engineering, and regenerative medicine. By providing the necessary environment for cell growth, feeder cells help scientists study cell behavior, explore cellular pathways, and develop potential therapeutic interventions.
Etymology of FEEDER CELL
The term "feeder cell" does not have a distinct etymology as it is a compound term that combines two separate words: "feeder" and "cell". Here is the etymology for each word:
1. Feeder: The word "feeder" originates from the Middle English word "fedar" (also spelled "federe") which means "someone or something that gives food". It is derived from the Old English word "fodrian", meaning "to feed" or "to nourish".
2. Cell: The word "cell" comes from the Latin word "cella" which means "small room" or "storeroom". It ultimately comes from the Proto-Indo-European root word "kel-", which signifies a concealed or hidden place.
