FBS Meaning and
Definition
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FBS stands for "Fetal Bovine Serum." It is a specialized component of cell culture media widely used in biomedical research and biotechnology applications. Fetal Bovine Serum is derived from the blood of unborn calves, specifically from the fetus after the mother cow has been slaughtered for meat production. FBS contains a complex mixture of growth factors, hormones, proteins, vitamins, and minerals necessary for supporting the growth and proliferation of cells in vitro.
The primary function of FBS in cell culture is to provide an optimal environment that mimics the conditions required for cells to proliferate and maintain their normal physiological functions. It acts as a nutrient-rich supplement, providing essential components such as amino acids, lipids, and vitamins that support cell growth and differentiation. FBS also acts as a reservoir of growth factors and cytokines that regulate cell signaling pathways and promote cell viability.
Researchers use FBS to sustain the growth of a variety of mammalian cells, including primary cells, established cell lines, and stem cells. It has become an integral component in various fields such as cancer research, drug discovery, regenerative medicine, and vaccine production. However, due to ethical concerns and the risk of transmitting infectious diseases, there has been a growing demand for alternative serum-free or animal-free culture media components. Nonetheless, FBS continues to be widely utilized in cell culture due to its high efficacy and established track record of supporting cell growth and viability.
Common Misspellings for FBS
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