How Do You Spell FAMILIAL HYPERCHOLESTEROLAEMIA?

Pronunciation: [famˈɪlɪəl hˌa͡ɪpəkˌə͡ʊlstəɹəlˈiːmi͡ə] (IPA)

Familial hypercholesterolaemia is a genetic condition that leads to high levels of cholesterol in the blood, increasing the risk of heart disease. The spelling of this word can be broken down using IPA phonetic transcription, which shows that the "f" is pronounced as the voiceless labiodental fricative [f]. The "a" is pronounced as the near-open front unrounded vowel [æ], while the "i" is pronounced as the close front unrounded vowel [ɪ]. The word ends with the suffix "-aemia," which represents the presence of a blood disorder.

FAMILIAL HYPERCHOLESTEROLAEMIA Meaning and Definition

1. Familial Hypercholesterolaemia (FH) is a genetic disorder characterized by abnormally high levels of cholesterol in the blood. It is an inherited condition that affects how the body processes and removes low-density lipoprotein (LDL) cholesterol, often referred to as "bad" cholesterol.

   Individuals with FH have a mutation in one of their genes responsible for controlling cholesterol metabolism. This mutation impairs the liver's ability to effectively remove LDL cholesterol from the bloodstream. As a result, LDL cholesterol accumulates, leading to elevated cholesterol levels and an increased risk of developing cardiovascular diseases like heart attacks and strokes at an early age.

   Symptoms of FH may not be apparent in childhood but can manifest later in life. These symptoms can include the presence of cholesterol deposits on tendons and under the skin, known as xanthomas, as well as the development of fatty deposits in the arteries called atherosclerosis.

   Diagnosis of FH is typically based on a combination of family history, physical examination, and blood tests that measure cholesterol levels and the presence of specific genetic mutations. Treatment options for individuals with FH involve lifestyle changes such as adopting a low-cholesterol diet, regular exercise, and avoiding smoking. Additionally, medications like statins and other cholesterol-lowering drugs may be prescribed to better regulate cholesterol levels. In severe cases, specific procedures like apheresis, which removes LDL cholesterol from the blood, may be necessary.

   Early detection and intervention are crucial to managing FH effectively and reducing the risk of cardiovascular complications. Regular monitoring, genetic testing, and collaboration between healthcare professionals and affected individuals and their families play a critical role in managing this hereditary condition.

Common Misspellings for FAMILIAL HYPERCHOLESTEROLAEMIA

• damilial hypercholesterolaemia
• camilial hypercholesterolaemia
• vamilial hypercholesterolaemia
• gamilial hypercholesterolaemia
• tamilial hypercholesterolaemia
• ramilial hypercholesterolaemia
• fzmilial hypercholesterolaemia
• fsmilial hypercholesterolaemia
• fwmilial hypercholesterolaemia
• fqmilial hypercholesterolaemia
• fanilial hypercholesterolaemia
• fakilial hypercholesterolaemia
• fajilial hypercholesterolaemia
• famulial hypercholesterolaemia
• famjlial hypercholesterolaemia
• famklial hypercholesterolaemia
• famolial hypercholesterolaemia
• fam9lial hypercholesterolaemia
• fam8lial hypercholesterolaemia
• famikial hypercholesterolaemia

Etymology of FAMILIAL HYPERCHOLESTEROLAEMIA

The term "familial hypercholesterolaemia" is a combination of three words: "familial", "hypercholesterolaemia", and "hypercholesterolemia", with the latter two words often used interchangeably.

1. Familial: The word "familial" is derived from the Latin word "familiālis", which means "pertaining to a family". It is used to describe conditions or traits that are hereditary and tend to occur within families.

2. Hypercholesterolaemia: The term "hypercholesterolaemia" is derived from Greek and Latin root words. "Hyper" means "excessive" or "above normal", "cholesterol" refers to a sterol compound found in the body, and "aemia" means "in the blood".

Plural form of FAMILIAL HYPERCHOLESTEROLAEMIA is FAMILIAL HYPERCHOLESTEROLAEMIAS