Fadrozole is a synthetic, non-steroidal compound that belongs to the class of aromatase inhibitors. It is primarily used in medical settings as a drug to inhibit the enzyme aromatase, which is responsible for the conversion of androgens (such as testosterone) into estrogens (such as estradiol). By blocking this conversion process, fadrozole effectively reduces the levels of estrogen in the body.
Used primarily in the treatment of hormone receptor-positive breast cancer, fadrozole has been shown to inhibit the growth of certain tumors by depriving them of estrogen, which is known to stimulate their growth. It is often prescribed in postmenopausal women who have already undergone surgical removal of the cancerous tissue or have had radiation therapy.
Additionally, fadrozole has also been evaluated for its potential use in enhancing fertility treatment outcomes. By suppressing estrogen production, it can help regulate hormone levels and promote ovulation in women experiencing fertility issues.
When taken orally, fadrozole is generally well-tolerated, with common side effects including hot flashes, headaches, and mild gastrointestinal disturbances. However, as with any medication, there may be rare occurrences of more severe adverse reactions, and it is important for patients to be under close medical supervision while taking fadrozole.
Overall, fadrozole is a pharmacological agent that works by inhibiting the production of estrogen, primarily used in the treatment of hormone receptor-positive breast cancer and potentially for enhancing fertility treatment outcomes.
