FACTOR VII Meaning and
Definition
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Factor VII is a term primarily used in the field of medicine and biochemistry, relating to a specific protein within the blood coagulation system. It refers to coagulation factor VII, an essential component of the intrinsic and extrinsic pathways in the process of blood clotting. Factor VII, also known as proconvertin, is a glycoprotein produced in the liver and circulates in the blood.
Functionally, factor VII acts as an enzyme, initiating the complex cascade of reactions necessary for hemostasis and clot formation. It plays a crucial role in initiating the extrinsic pathway by binding with tissue factor, a membrane glycoprotein found on damaged vessels, and forming a complex. This complex activates factor X, which subsequently triggers the clotting cascade.
Deficiencies or abnormalities in factor VII can have significant clinical implications, leading to bleeding disorders or excessive clotting. Deficiency in factor VII can arise due to genetic mutations, liver disease, or vitamin K deficiency. Individuals with factor VII deficiency may present with prolonged bleeding, easy bruising, or abnormal bleeding after injury or surgery.
Factor VII is also utilized therapeutically as a medication known as recombinant factor VIIa (rFVIIa) to treat inherited or acquired bleeding disorders, particularly in patients with hemophilia or other coagulation defects. rFVIIa acts by directly binding with tissue factor to stimulate thrombin generation, thereby promoting clot formation and preventing excessive bleeding.
In summary, factor VII is a protein that initiates the clotting cascade in the blood coagulation system, crucial for maintaining hemostasis.
Common Misspellings for FACTOR VII
- dactor vii
- cactor vii
- vactor vii
- gactor vii
- tactor vii
- ractor vii
- fzctor vii
- fsctor vii
- fwctor vii
- fqctor vii
- faxtor vii
- favtor vii
- faftor vii
- fadtor vii
- facror vii
- facfor vii
- facgor vii
- facyor vii
- fac6or vii
Etymology of FACTOR VII
The term "factor VII" is derived from several components:
1. Factor: In the context of blood coagulation, a factor refers to a protein that plays a role in the clotting process. In the early days of research on blood clotting, various clotting factors were identified and numbered in the order of their discovery.
2. VII: The Roman numeral "VII" represents the number 7. Factor VII specifically refers to the seventh clotting factor that was discovered and characterized.
So, the term "factor VII" simply indicates the presence of the seventh clotting factor in the coagulation cascade.
Similar spelling words for FACTOR VII
- factor viii,
- factor i,
- factor in,
- factor iii,
- factor iv,
- factor out,
- factorisation,
- factory price,
- factor ix,
- factorize,
- factoring,
- factorise,
- factorial,
- factor v,
- factory,
- factor xi,
- factor xii,
- factor x,
- factory ship,
- factorization,
- factor ii,
- factor xiii.
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