How Do You Spell FACTOR D?

Pronunciation: [fˈaktə dˈiː] (IPA)

Factor D is a protein that plays a key role in the complement system, a part of the immune system that helps to defend against infections. The spelling of Factor D is quite straightforward, with the IPA phonetic transcription for the word being /ˈfæktər diː/. This means that the word is pronounced "fak-tuh dee", with the stress falling on the first syllable. The "D" in the name refers to the fourth protein identified in the complement system's alternative pathway.

FACTOR D Meaning and Definition

1. Factor D is a critical protein component of the complement system, a part of the immune response that helps the body in identifying and eliminating harmful pathogens. It is an enzyme that plays a key role in the alternative pathway of the complement system, which is one of the three pathways involved in the activation of the complement cascade.

   Specifically, Factor D acts as a serine protease that cleaves Factor B, another protein of the complement system, into two fragments: Ba and Bb. This enzymatic activity results in the activation of Factor Bb, which then combines with other complement factors to form a complex known as C3 convertase generating C3b. The alternative pathway amplifies the immune response and enhances the opsonization of foreign substances, marking them for removal by immune cells.

   Factor D is primarily produced by the liver and, once activated, circulates in the blood stream. Deficiencies in Factor D have been associated with an increased susceptibility to infections, particularly with Neisseria species, suggesting its critical role in host defense against these pathogens. Moreover, dysregulation of Factor D activity has been implicated in various autoimmune diseases and inflammatory conditions.

   Overall, Factor D is an essential protein of the complement system that acts as a serine protease, participating in the alternative pathway and contributing to the immune response against infections and other pathological processes.

Common Misspellings for FACTOR D

• dactor d
• cactor d
• vactor d
• gactor d
• tactor d
• ractor d
• fzctor d
• fsctor d
• fwctor d
• fqctor d
• faxtor d
• favtor d
• faftor d
• fadtor d
• facror d
• facfor d
• facgor d
• facyor d
• fac6or d
• fac5or d

Etymology of FACTOR D

The word "Factor D" does not have a separate etymology, as it is a technical term used in the field of immunology and biochemistry. So, it does not have a specific origin or derivation. However, it is worth noting that the "D" in Factor D refers to the fourth component discovered in the complement system, a part of the immune system.