How Do You Spell EXTRACELLULAR SIGNAL REGULATED KINASES?

Pronunciation: [ˌɛkstɹəsˈɛljʊlə sˈɪɡnə͡l ɹˈɛɡjuːlˌe͡ɪtɪd kˈɪne͡ɪsɪz] (IPA)

Extracellular Signal Regulated Kinases (ERKs) are an important family of enzymes involved in various cellular signalling pathways. The word is pronounced as ['ɛkstrəˈsɛljʊlər] [ˈsɪɡnəl] [ˈɹɛɡjʊleɪtɪd] [ˈkɪnəzeɪz]. The IPA phonetic transcription reveals that "extracellular" is pronounced with the stress on the second syllable and the "c" is softly pronounced as an "s". "Regulated" is pronounced with the stress on the second syllable and the "g" is sounded like a "j". "Kinases" is pronounced with the stress on the first syllable and the final "s" is pronounced as a "z".

EXTRACELLULAR SIGNAL REGULATED KINASES Meaning and Definition

  1. Extracellular Signal Regulated Kinases (ERKs) are a type of protein kinase enzyme that play a crucial role in intracellular signal transduction pathways. They are a part of the mitogen-activated protein kinase (MAPK) family, which includes several other kinases responsible for transmitting signals from the cell surface to the nucleus.

    ERKs are activated in response to various extracellular stimuli, such as growth factors, hormones, and stress signals. Once activated, they phosphorylate and regulate the activity of numerous downstream targets, including other kinases, transcription factors, and cytoskeletal proteins. This ultimately leads to a cascade of cellular responses, such as cell proliferation, differentiation, survival, and apoptosis.

    The ERK signaling pathway is highly conserved across different species and is involved in diverse cellular processes, including development, immune responses, and memory formation. Dysregulation of ERK signaling has been implicated in several diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

    The activation of ERKs occurs through a series of phosphorylation events, typically involving the sequential activation of kinases in a signaling cascade. ERKs are initially phosphorylated by upstream kinases known as MAPK kinases (MEKs), which are themselves activated by various upstream signaling molecules. Once activated, the phosphorylated ERKs translocate to the nucleus and phosphorylate their downstream targets, leading to the modulation of gene expression and cellular responses.

    In summary, Extracellular Signal Regulated Kinases (ERKs) are a class of protein kinases that play a vital role in transmitting signals from the cell surface to the nucleus. They are involved in various cellular processes and have significant implications in health and disease.

Common Misspellings for EXTRACELLULAR SIGNAL REGULATED KINASES

  • wxtracellular signal regulated kinases
  • sxtracellular signal regulated kinases
  • dxtracellular signal regulated kinases
  • rxtracellular signal regulated kinases
  • 4xtracellular signal regulated kinases
  • 3xtracellular signal regulated kinases
  • eztracellular signal regulated kinases
  • ectracellular signal regulated kinases
  • edtracellular signal regulated kinases
  • estracellular signal regulated kinases
  • exrracellular signal regulated kinases
  • exfracellular signal regulated kinases
  • exgracellular signal regulated kinases
  • exyracellular signal regulated kinases
  • ex6racellular signal regulated kinases
  • ex5racellular signal regulated kinases
  • exteacellular signal regulated kinases
  • extdacellular signal regulated kinases
  • extfacellular signal regulated kinases
  • exttacellular signal regulated kinases

Infographic

Add the infographic to your website: