EVENT FREE SURVIVAL Meaning and
Definition
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Event-free survival (EFS) refers to a medical term used in clinical research and healthcare, specifically in the context of assessing the outcomes of patients in various treatment or intervention settings. It is a measure used to analyze and evaluate the length of time a patient survives or remains free from certain predefined events, complications, or adverse outcomes after a particular medical treatment or intervention.
This term is commonly utilized in oncology and cardiology research, where it is essential to determine the impact of specific treatments on patients' overall survival without experiencing significant events or complications. These events may refer to disease progression, recurrence, relapse, adverse side effects, hospitalization, or even death. EFS provides substantial insights into the effectiveness of a treatment or intervention by examining if it has provided patients with a prolonged period of being free from such events.
The determination of EFS is usually done through comprehensive and regular follow-up assessments, such as medical examinations, laboratory tests, imaging studies, or patient-reported outcomes. The length of event-free survival is typically measured from the start of treatment or intervention until the occurrence of a defined event or a specified time point. EFS is an important endpoint in clinical trials, as it provides a holistic perspective on the impact of interventions by focusing on the absence of specific adverse events, rather than solely considering overall survival or treatment response.
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