EUGLYCAEMIC CLAMP Meaning and
Definition
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The euglycaemic clamp is a widely recognized and valuable tool used in medical research and clinical settings to measure the body's response to insulin and glucose regulation. This technique involves establishing a stable and normal blood glucose level, also known as euglycaemia, through continuous glucose infusion or ingestion.
During an euglycaemic clamp procedure, a fixed amount of glucose is infused intravenously to maintain a stable blood glucose concentration while insulin is simultaneously administered. This allows researchers or healthcare professionals to measure the body's insulin sensitivity and accurately assess the effectiveness of various interventions or treatments.
The euglycaemic clamp provides precise information about the body's glucose metabolism by determining the amount of glucose needed to maintain euglycaemia while insulin levels are manipulated. This technique allows for the measurement of key parameters, including glucose disposal rate, insulin clearance rate, and insulin sensitivity index.
Researchers and healthcare professionals commonly use the euglycaemic clamp to evaluate insulin resistance in individuals with diabetes or other metabolic disorders. It is also frequently employed in pharmaceutical studies to assess the effectiveness of new drugs aimed at improving glucose regulation.
Overall, the euglycaemic clamp provides valuable insights into the body's ability to regulate glucose and insulin, aiding in the diagnosis, monitoring, and treatment of conditions related to glucose metabolism.
Common Misspellings for EUGLYCAEMIC CLAMP
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- eugpycaemic clamp
Etymology of EUGLYCAEMIC CLAMP
The word "Euglycaemic Clamp" is a combination of two terms: "euglycemia" and "clamp".
1. Euglycemia: The prefix "eu-" means "good" or "normal", and "glycemia" refers to the concentration of glucose in the blood. Therefore, "euglycemia" means maintaining normal blood glucose levels.
2. Clamp: In medical research procedures, a "clamp" refers to a technique used to maintain a certain physiological parameter at a constant level. It involves manipulating certain variables to ensure the desired parameter remains stable.
In the context of medical and scientific research, a euglycaemic clamp is a technique used to maintain a stable blood glucose level throughout an experiment or study. It involves continuously monitoring and adjusting the glucose infusion rate to counteract any changes in blood glucose levels, essentially "clamping" it at the desired normal level.
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