Esthiomenous is a rare and complex word that is difficult to spell correctly without an understanding of its pronunciation. In IPA (International Phonetic Alphabet), the word is spelled /ɛsθiɒmɛnəs/. This word has a combination of two difficult letter combinations, "st" and "th," which are pronounced differently. The "st" is pronounced as a cluster of two consonant sounds, while the "th" is pronounced with the tongue between the teeth. Though rarely used, knowing the correct spelling and pronunciation of esthiomenous can be useful for those studying linguistics.
Corroding, ulcerating, phagedenic.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.