How Do You Spell ERYTHROPOIETIC PORPHYRIA?

Pronunciation: [ˌɜːɹɪθɹˌɒpɔ͡ɪˈɛtɪk pɔːfˈɪɹi͡ə] (IPA)

Erythropoietic Porphyria is a rare genetic disease that affects the production of heme, a component of red blood cells. The word "Erythropoietic" is spelled [əˌrɪθroʊˈpɔɪɛtɪk], with the stress on the third syllable. The "th" in "rithro-" is pronounced as a voiced dental fricative [ð] instead of a voiceless dental fricative [θ]. The word "Porphyrin" is spelled [pɔrˈfɪrɪn], with the stress on the first syllable. This disease is also known as "Günther's Disease" after the German physician who first described it.

ERYTHROPOIETIC PORPHYRIA Meaning and Definition

1. Erythropoietic porphyria is a rare genetic disorder that affects the synthesis of heme, a vital component of hemoglobin, the protein responsible for carrying oxygen in red blood cells. This condition belongs to a group of disorders known as porphyrias that result from abnormalities in the production of porphyrins, the precursors of heme.

   In erythropoietic porphyria, there is a deficiency or dysfunction of the enzyme uroporphyrinogen III synthase, which leads to the accumulation of porphyrins in the body. The excess porphyrins can build up in the skin, causing photosensitivity and resulting in severe sunburn-like rashes upon exposure to sunlight. The accumulation of porphyrins can also affect other body tissues, leading to a variety of symptoms.

   Individuals with erythropoietic porphyria may experience chronic anemia due to hemolysis, the breakdown of red blood cells, and the impairment of heme production. Other common symptoms can include abdominal pain, dark urine, liver dysfunction, and growth abnormalities. Furthermore, some individuals may develop complications such as gallstones, scarring of the skin, or infections.

   Diagnosis of erythropoietic porphyria typically involves a combination of clinical presentation, biochemical testing, and genetic analysis. Treatment options for this condition are limited and primarily focus on managing symptoms and preventing complications. Measures such as avoiding sun exposure, using protective clothing or sunscreen, and taking supplements to maintain sufficient levels of heme may help minimize symptoms and reduce the risk of complications.

   In summary, erythropoietic porphyria is a rare inherited disorder characterized by a deficiency of the enzyme uroporphyrinogen III synthase, resulting in the accumulation of porph

Common Misspellings for ERYTHROPOIETIC PORPHYRIA

• wrythropoietic porphyria
• srythropoietic porphyria
• drythropoietic porphyria
• rrythropoietic porphyria
• 4rythropoietic porphyria
• 3rythropoietic porphyria
• eeythropoietic porphyria
• edythropoietic porphyria
• efythropoietic porphyria
• etythropoietic porphyria
• e5ythropoietic porphyria
• e4ythropoietic porphyria
• ertthropoietic porphyria
• ergthropoietic porphyria
• erhthropoietic porphyria
• eruthropoietic porphyria
• er7thropoietic porphyria
• er6thropoietic porphyria
• eryrhropoietic porphyria
• eryfhropoietic porphyria

Etymology of ERYTHROPOIETIC PORPHYRIA

The word "erythropoietic porphyria" is composed of two main parts: "erythropoietic" and "porphyria".

1. Erythropoietic: The term "erythropoietic" comes from the Greek words "erythros" meaning "red" and "poiesis" meaning "making" or "production". In the context of erythropoietic porphyria, "erythropoietic" refers to the disorder's effect on the production of red blood cells.

2. Porphyria: The term "porphyria" derives from the Greek word "porphyra" which means "purple". The name "porphyria" was given to the disorder due to the purple or reddish-brown color of urine during an acute attack.