Erythroblastosis Fetalis is a medical condition that affects the blood of newborn infants. The word "Erythroblastosis" comes from the Greek word "erythros" meaning red, and "blastos" meaning germ or cell. The pronunciation of "erythroblastosis" is /ɛˌrɪθroʊblæsˈtoʊsɪs/. "Fetalis" means related to or affecting the fetus, and its pronunciation is /fɪˈteɪlɪs/. The correct spelling of this medical term is important for healthcare professionals as it ensures clear communication and accurate diagnosis of the condition.
Erythroblastosis fetalis, also known as hemolytic disease of the newborn, is a condition that occurs when a pregnant woman's blood type is incompatible with that of her fetus. Specifically, it is characterized by an immune response in which the mother's antibodies cross the placenta and attack the red blood cells of the fetus.
The condition typically arises when a mother with Rh-negative blood type carries a fetus with Rh-positive blood type. However, it can also occur in other blood type incompatibilities such as ABO or other antigens.
Erythroblastosis fetalis occurs when the mother has been previously sensitized to the Rh antigen, usually through previous pregnancies or blood transfusions. Sensitization leads to the production of antibodies against the Rh antigen, which can cross the placenta and target the fetal red blood cells. The destruction of these cells leads to a decrease in oxygen-carrying capacity and can result in anemia, jaundice, and, in severe cases, fetal death.
The severity of erythroblastosis fetalis varies, with mild cases often showing minimal symptoms while severe cases can cause life-threatening complications. Treatment involves close monitoring of the fetus during pregnancy and, if necessary, various interventions such as intrauterine blood transfusions, phototherapy, or early delivery. To prevent erythroblastosis fetalis, Rh-negative mothers are administered an injection of Rh immunoglobulin during pregnancy and within 72 hours after delivery or any other potential sensitizing event to prevent the development of antibodies.
The word "Erythroblastosis Fetalis" is derived from Greek and Latin roots. Here is a breakdown of each component:
1. Erythroblastosis:
- "Erythro-" comes from the Greek word "erythros" meaning "red".
- "-blast-" comes from the Greek word "blastos" meaning "germ" or "bud".
- "-osis" is a suffix in Greek and Latin used to indicate a condition or state.
So, "Erythroblastosis" can be roughly defined as the condition or state of having red blood cell germs or immature red blood cells.
2. Fetalis:
- "Fetalis" is derived from the Latin word "fetus" meaning "offspring" or "young one". It specifically refers to an unborn or newly born offspring.