The correct spelling of the word "ergotinic acid" is [ɜː(r)ˈɡɒtɪnɪk ˈæsɪd]. The first syllable "er" is pronounced with a schwa sound, followed by the "g" sound and an "o" pronounced as a short vowel. The second syllable is "tin" pronounced with a short "i" sound. The third syllable "ic" is pronounced with a long "i" sound. Finally, the last two syllables "acid" are pronounced as they are spelled. Ergotinic acid is a medication used to treat migraines and cluster headaches.
Ergotinic acid is a natural substance that belongs to the class of organic compounds known as organic acids. It is derived from the ergot fungus, particularly from the sclerotium of the fungus. This fungus, scientifically known as Claviceps purpurea, infects grains such as rye and barley, leading to a condition called ergotism in humans and animals consuming contaminated grain.
Chemically, ergotinic acid is classified as a derivate of lysergic acid, which represents the main building block for numerous similar compounds. It possesses a chemical structure consisting of a fused tetracyclic ring system, making it structurally related to various alkaloids including ergotamine and ergonovine.
Ergotinic acid has been primarily studied for its physiological and pharmacological effects. It exhibits vasoconstrictive properties and has been used in the treatment of migraines and other types of headaches. Additionally, ergotinic acid has been investigated for its involvement in the biosynthesis of ergot alkaloids and its potential as a precursor or intermediate in the chemical synthesis of these compounds.
As an organic acid, ergotinic acid can undergo chemical reactions characteristic of carboxylic acids. It can form salts, esters, and amides, displaying different chemical and biological properties depending on the specific derivatives formed. Overall, ergotinic acid plays a significant role in the understanding and exploration of ergot alkaloids' biosynthesis and their medicinal applications.
Ergotic acid, a light brown amorphous powder, decomposed by the gastric juice, but actively hemostatic when given by hypodermic injection.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "ergotinic acid" is derived from two main components:
1. Ergot: The term "ergot" originates from the Middle French word "argot", which means "spur" or "cockspur". This is because ergot resembles a spur or projection that grows on various grains, particularly rye. The term was later anglicized to "ergot". The fungus that produces ergot contains various biologically active compounds, including ergotamine, from which ergotinic acid is derived.
2. -ic acid: The suffix "-ic acid" is added to the noun "ergot" to form "ergotinic acid". "-ic acid" is a common naming convention for organic compounds with carboxylic acid functional groups. It indicates that the substance is an acid derived from the original noun or compound.