EPITHELIAL BODIES Meaning and
Definition
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Epithelial bodies, also referred to as corpuscles or Hassall's corpuscles, are small, round structures found within the thymus gland. They are named after their discoverer, Arthur Hill Hassall, an English physician and microscopist from the 19th century. These bodies are primarily composed of concentric layers of keratinized epithelial cells that form a rounded or irregularly shaped structure.
Epithelial bodies are more commonly found in the medulla (inner region) of the thymus gland and are absent or scarce in the cortical regions. They typically range in size from 20 to 400 micrometers and are often clustered together. The exact function and significance of epithelial bodies are still not fully understood, although several theories have been proposed.
One widely accepted theory suggests that epithelial bodies play a role in the formation and maturation of T-lymphocytes, which are crucial for immune responses. They are believed to be involved in the negative selection process, which ensures that only T-cells with proper recognition of self-antigens are allowed to mature and enter the bloodstream. Epithelial bodies are also considered as sites of antigen-presenting cells, controlling the release of cytokines and growth factors that further regulate the development and function of immune cells.
In summary, epithelial bodies are distinct structures within the thymus gland, consisting of concentric layers of keratinized epithelial cells. Though their exact function is not fully understood, they are believed to have roles in T-lymphocyte maturation, negative selection, and immune regulation.
Common Misspellings for EPITHELIAL BODIES
- Epithelial Bodie
- Epithelial Bodys
- Epithelial Bodyes
- epithial bodies
- epithelical bodies
- epithelials bodies
- epitheleal bodies
- epithelium bodies
Etymology of EPITHELIAL BODIES
The word "epithelial" derives from the Greek word "epithelium", meaning "a covering" or "outercoat". "Epithelium" is a combination of "epi", meaning "upon", and "thēlē", meaning "nipple" or "nipple-like". The term "epithelial" refers to the type of tissue that covers the surfaces and lines the cavities of organs and structures in the body.
The term "bodies" in "epithelial bodies" refers to structures or masses in the body. It is a general term used to describe specialized anatomical structures, organs, or clusters of cells within an organ.
Therefore, "epithelial bodies" suggests structures or masses that are composed of epithelial tissue.
