EPCAM Meaning and
Definition
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EPCAM is an acronym that stands for epithelial cell adhesion molecule. It is a transmembrane glycoprotein involved in cell-cell adhesion. EPCAM is primarily expressed on the surface of epithelial cells, which are the cells that line various structures and organs in the body. Due to its role in cell adhesion, EPCAM plays a crucial role in maintaining the structural integrity and function of epithelial tissues.
The EPCAM protein is encoded by the EPCAM gene, which is located on chromosome 2. Mutations or abnormalities in the EPCAM gene can lead to altered expression or function of the protein, contributing to various diseases and conditions. For example, abnormal expression of EPCAM has been observed in certain types of cancer, such as colorectal, ovarian, and breast cancers, where it is often overexpressed. In these cases, EPCAM can serve as a useful biomarker for the detection and diagnosis of cancer, as well as a potential target for therapeutic interventions.
In addition to its role in cell adhesion, EPCAM has also been implicated in cell signaling pathways, cell differentiation, and tissue regeneration. It is involved in intercellular communication and has been shown to interact with other proteins and molecules in the cell membrane. Further research is still needed to fully elucidate the exact mechanisms and functions of EPCAM in different physiological and pathological processes.
Common Misspellings for EPCAM
- epcanm
- epcamn
- epcakm
- epcamk
- epcajm
- epcamj
- eepcam
- epccam
- epcaam
- epcamm
- uPCAM
- mPCAM
- gPCAM
- EtCAM
- EqCAM
- EPkAM
- EPCiM
- EPCAi
- EPCAo
- epca m
