ENZYME REPLACEMENT Meaning and
Definition
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Enzyme replacement refers to a therapeutic approach used in medicine to treat certain genetic disorders known as enzyme deficiencies. Enzymes are proteins that catalyze or speed up chemical reactions in cells and are essential for various biological processes.
In individuals with enzyme deficiencies, the body is unable to produce enough of a particular enzyme, or the enzyme may be non-functional. This can lead to the accumulation of toxic substances, as these enzymes are crucial for breaking down and metabolizing certain compounds. Without a sufficient supply of the necessary enzyme, the body's normal functioning can be impaired.
Enzyme replacement therapy aims to address this deficiency by introducing the missing or malfunctioning enzyme into the body. The treatment involves administering a synthetic or bioengineered version of the enzyme directly into the bloodstream or affected tissues. The replacement enzymes then circulate or distributed throughout the body, contributing to the deficient enzyme's activity.
This therapy is typically administered on a regular basis, usually through intravenous infusion or injection, depending on the type and severity of the deficiency being treated. Enzyme replacement therapy has been successful in managing various conditions, such as Gaucher's disease and Fabry disease, by reducing the buildup of harmful substances and alleviating associated symptoms.
Enzyme replacement therapy has revolutionized the treatment of enzyme deficiencies, providing individuals with these genetic disorders a means to manage their conditions better and improve their quality of life.
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