EDROPHONIUM BROMIDE Meaning and
Definition
-
Edrophonium bromide is a pharmaceutical compound used as a diagnostic agent in medicine. It belongs to a class of drugs known as acetylcholinesterase inhibitors, which work by inhibiting the action of the enzyme acetylcholinesterase. This enzyme is responsible for breaking down the neurotransmitter acetylcholine in the synaptic cleft, which is crucial for the normal functioning of the nervous system.
The primary purpose of using edrophonium bromide is to diagnose myasthenia gravis, a neuromuscular disorder characterized by muscle weakness and fatigue. It is administered intravenously and works by temporarily improving muscle strength in individuals with this condition. This improvement is known as the edrophonium test or the Tensilon test.
Edrophonium bromide is rapidly hydrolyzed within the body and has a short half-life, making it suitable for diagnostic purposes. Its effects typically last only a few minutes, allowing for observation of any improvements in muscle strength. This test is helpful in distinguishing myasthenia gravis from other conditions that cause similar symptoms.
In addition to its diagnostic use, edrophonium bromide has also been used as a therapeutic drug in the past for myasthenia gravis, although other more effective medications have largely replaced it in this role.
It is important to note that edrophonium bromide should only be used under the supervision of a qualified healthcare professional, as it may have side effects such as nausea, vomiting, salivation, and bradycardia in some individuals.
Common Misspellings for EDROPHONIUM BROMIDE
- wdrophonium bromide
- sdrophonium bromide
- ddrophonium bromide
- rdrophonium bromide
- 4drophonium bromide
- 3drophonium bromide
- esrophonium bromide
- exrophonium bromide
- ecrophonium bromide
- efrophonium bromide
- errophonium bromide
- eerophonium bromide
- edeophonium bromide
- eddophonium bromide
- edfophonium bromide
- edtophonium bromide
- ed5ophonium bromide
- ed4ophonium bromide
- edriphonium bromide
- edrkphonium bromide
Etymology of EDROPHONIUM BROMIDE
The word "Edrophonium" is derived from a combination of two components: "Edro-" and "-phonium".
The "Edro-" part is derived from "Edrophonium's" predecessor drug called "Edrine". "Edrine" is a contraction of "Ethylene Diamine Rhodanide". "Ethylene" refers to a hydrocarbon compound, "diamine" represents a molecule containing two amine groups, and "rhodanide" refers to the specific chemical compound known as "sodium rhodanide".
The "-phonium" ending refers to a class of synthetic organic compounds called "quaternary ammonium". These compounds are characterized by a positively charged nitrogen atom and are often used in pharmaceutical drugs.
The addition of "Bromide" at the end of "Edrophonium" refers to the specific chemical compound "bromide".
