The spelling of the name Dwain is quite straightforward when using IPA phonetic transcription. The first syllable is pronounced /dweɪn/, with the "d" sound followed by the diphthong "ei" (as in "weigh" or "hey"). The second syllable is pronounced as /eɪn/, like the word "cane" or "pain". Overall, the pronunciation of Dwain is similar to the name Duane or Dwayne, but with a slightly different spelling.
The name "Dwain" is of Welsh origin, derived from the Welsh name "Dwyn", which means "worthy" or "blessed". It is a variant of the Welsh name "Dwynwen", which is a combination of "dwyn" meaning "fair" or "white", and "gwen" meaning "blessed" or "pure". "Dwain" became popular as a given name in the United States during the 20th century.