Drug hypersensitivity, pronounced /drʌg hʌɪpəsɛnsɪˈtɪvɪti/, refers to an exaggerated immune response elicited by exposure to a certain medication. The spelling of this term is derived from the combination of two words - drug and hypersensitivity. The IPA phonetic transcription helps to break down the syllables and sounds of each letter, aiding in correct pronunciation. Understanding the correct spelling and pronunciation of drug hypersensitivity is crucial for healthcare professionals in identifying adverse drug reactions and providing appropriate patient care.
Drug hypersensitivity refers to an abnormal reaction of the immune system towards a drug or medication. It is a type of adverse drug reaction that occurs when the immune system identifies a particular drug as foreign or harmful, leading to an exaggerated response that can result in various symptoms and complications.
When someone experiences drug hypersensitivity, their immune system produces an excessive immune response to the drug, even at therapeutic doses. This immune response could manifest as allergic reactions, including skin rashes, itching, hives, or swelling of the face, lips, or tongue. In severe cases, drug hypersensitivity can result in a life-threatening condition known as anaphylaxis, characterized by difficulty breathing, low blood pressure, and rapid heartbeat.
The development of drug hypersensitivity is influenced by several factors, including genetic predisposition, duration and frequency of drug exposure, and the individual's immune system function. It is important to note that drug hypersensitivity differs from drug intolerance or side effects, which are more common and typically not immune-mediated.
Diagnosis of drug hypersensitivity involves a detailed medical history, physical examination, and sometimes additional diagnostic tests such as skin tests or drug provocation tests. Treatment primarily focuses on discontinuing the use of the drug causing the hypersensitivity reaction and providing symptomatic relief. In severe cases, emergency medical intervention may be necessary.
It is essential for individuals with known drug hypersensitivity to inform healthcare professionals about their specific medication allergies to avoid potential adverse reactions and ensure safer alternative treatment options when necessary.
The word "drug" originated from the Middle English word "drogge", which meant "medicine or chemical substance". This Middle English term came from the Old French word "drogue", which referred to a "therapeutic substance" or "medicinal plant". The ultimate source of the word is believed to be the Dutch word "droge", meaning "dry".
"Hypersensitivity" is a compound word formed from the prefix "hyper-" meaning "over" or "excessive", and the word "sensitivity" derived from the Latin word "sensibilitas".
Therefore, "drug hypersensitivity" can be broken down into "drug", referring to a medicinal substance, and "hypersensitivity", indicating an excessive or heightened response to that substance.