DOXORUBICIN Meaning and
Definition
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Doxorubicin is a potent and widely used chemotherapy drug that belongs to the class of anthracyclines. It is an antibiotic and an antineoplastic agent primarily used in the treatment of various types of cancer, including breast cancer, bladder cancer, lung cancer, and ovarian cancer, among others. Doxorubicin is typically administered intravenously and works by inhibiting the proliferation of cancer cells.
The drug works by intercalating with DNA, specifically targeting the enzyme topoisomerase II, which is responsible for repairing DNA damage and facilitating DNA replication. By inhibiting this enzyme, doxorubicin prevents the DNA from unwinding and hinders the ability of cancer cells to divide and replicate. Additionally, doxorubicin generates free radicals which contribute to its cytotoxic effects, further damaging the cancer cells.
Although doxorubicin is highly effective in many cancer treatments, it is associated with potential side effects, such as nausea, vomiting, hair loss, decreased blood cell counts, and increased susceptibility to infections. To minimize the risk of cardiotoxicity, which is a serious concern associated with doxorubicin, the drug is often administered in controlled doses and monitored closely.
In conclusion, doxorubicin is a potent chemotherapy drug that is widely used in the treatment of various types of cancer. By targeting and inhibiting the replication machinery of cancer cells, it displays anticancer activity. Careful dosage management and monitoring are necessary to balance its therapeutic benefits against potential side effects.
Common Misspellings for DOXORUBICIN
- soxorubicin
- xoxorubicin
- coxorubicin
- foxorubicin
- roxorubicin
- eoxorubicin
- dixorubicin
- dkxorubicin
- dlxorubicin
- dpxorubicin
- d0xorubicin
- d9xorubicin
- dozorubicin
- docorubicin
- dodorubicin
- dosorubicin
- doxirubicin
- doxkrubicin
- doxlrubicin
- doxprubicin
Etymology of DOXORUBICIN
The word "doxorubicin" is derived from its chemical structure and components. It is a combination of the term "doxo-" and "rubicin".
The "doxo-" prefix refers to the molecule's anthracycline structure, which includes an anthraquinone chromophore. This structural feature gives the molecule its unique chemical and biological properties.
The "-rubicin" suffix is borrowed from the word "rubidomycin", an early anthracycline antibiotic derived from Streptomyces cultures. Doxorubicin was originally developed as a modification of the rubidomycin compound, hence the use of the "-rubicin" term in its name.
Therefore, the etymology of "doxorubicin" highlights its chemical composition and revision from the rubidomycin structure.
