DNA LESION Meaning and
Definition
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A DNA lesion refers to any structural alteration or damage that occurs in the DNA molecule, typically resulting from various external factors or internal errors during replication or repair processes. The DNA molecule is composed of two strands twisted together in a double helix configuration, and it serves as the genetic blueprint for all living organisms.
DNA lesions can arise due to a variety of causes, including exposure to harmful chemicals, radiation, ultraviolet light, or even errors made by enzymes involved in DNA replication and repair. These lesions can manifest in several forms, such as changes in the DNA sequence (mutations), breaks in the DNA strands, or modifications to DNA bases or sugars.
The presence of DNA lesions can have profound implications for the cell or organism as these alterations can disrupt the normal functioning and structure of DNA. Lesions can interfere with critical cellular processes, including DNA replication, transcription, and translation, which are essential for proper cell function. If left unrepaired, DNA lesions can lead to permanent changes in the genetic code, potentially resulting in genetic disorders, diseases, or even cancer.
To counteract the harmful effects of DNA lesions, cells have evolved sophisticated repair mechanisms that can detect and correct the lesions. Repair mechanisms include excision repair, mismatch repair, and direct reversal. These processes help to restore the integrity of the DNA molecule and preserve the accurate transmission of genetic information.
Common Misspellings for DNA LESION
- sna lesion
- xna lesion
- cna lesion
- fna lesion
- rna lesion
- ena lesion
- dba lesion
- dma lesion
- dja lesion
- dha lesion
- dnz lesion
- dns lesion
- dnw lesion
- dnq lesion
- dna kesion
- dna pesion
- dna oesion
- dna lwsion
- dna lssion
- dna ldsion
Etymology of DNA LESION
The term "DNA lesion" has its origin in two different sources.
Firstly, "DNA" stands for deoxyribonucleic acid, which is the genetic material found in nearly all living organisms. The term was coined by Friedrich Miescher, a Swiss biochemist, who discovered what he termed "nuclein" in 1869. Later, the substance was identified as DNA, and the term has been widely used ever since.
Secondly, "lesion" originated from the Latin word "laesionem", which means an injury or wound. It refers to any abnormal change or damage that occurs in the structure or function of an organ or tissue.
When combined, the term "DNA lesion" signifies any kind of damage or abnormality that occurs in the DNA molecule.
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