DNA FRAGMENTATION Meaning and
Definition
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DNA fragmentation refers to the process of breaking the DNA molecules into smaller fragments. DNA, or deoxyribonucleic acid, is the genetic material that carries the instructions for the development, functioning, and reproduction of all living organisms. In certain situations, such as during apoptosis (programmed cell death) or DNA damage, DNA fragmentation occurs as a result of the cleavage of DNA strands at specific sites by various enzymes.
DNA fragmentation can be measured and quantified using techniques such as gel electrophoresis, terminal deoxynucleotidyl transferase dUTP nick-end labeling (TUNEL), or comet assay. These techniques allow the visualization and estimation of the extent of DNA fragmentation by analyzing the size distribution of DNA fragments.
DNA fragmentation plays a crucial role in various biological processes. During apoptosis, which is a controlled and orderly form of cell death, DNA fragmentation occurs as a result of specific cleavage at nucleosomal internucleosomal sites. This fragmentation is an essential step in the degradation and subsequent removal of the dying cell.
DNA fragmentation can also be used as a marker for assessing the quality of sperm in fertility testing. High levels of DNA fragmentation in sperm may indicate certain conditions or factors that could affect fertility or the success of reproductive technologies.
Overall, DNA fragmentation refers to the fragmentation or breakage of DNA strands into smaller fragments, which can have important implications in areas such as cell death, DNA damage, and reproductive health.
Common Misspellings for DNA FRAGMENTATION
- sna fragmentation
- xna fragmentation
- cna fragmentation
- fna fragmentation
- rna fragmentation
- ena fragmentation
- dba fragmentation
- dma fragmentation
- dja fragmentation
- dha fragmentation
- dnz fragmentation
- dns fragmentation
- dnw fragmentation
- dnq fragmentation
- dna dragmentation
- dna cragmentation
- dna vragmentation
- dna gragmentation
- dna tragmentation
- dna rragmentation
Etymology of DNA FRAGMENTATION
The word "DNA fragmentation" is derived from the respective etymology of its constituent words, "DNA" and "fragmentation".
- DNA: DNA stands for Deoxyribonucleic Acid. The term "DNA" was coined by Swiss biochemist Johannes Friedrich Miescher in 1869. It is derived from the Greek words "deoxyribo-" meaning "resembling sugar" and "-nucleic acid" referring to its nucleic acid composition.
- Fragmentation: The term "fragmentation" is derived from the Latin word "fragmentum", meaning "a piece broken off or detached". It is commonly used to describe the process or action of breaking or dividing something into fragments or smaller parts.
So, "DNA fragmentation" refers to the breaking or dividing of DNA into smaller fragments or pieces.
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