How Do You Spell DIZOCILPINE MALEATE?

Pronunciation: [dˈɪzəsˌɪlpa͡ɪn mˈe͡ɪle͡ɪt] (IPA)

Dizocilpine Maleate, also known by its brand name, MK-801, is a drug used in scientific research. The spelling of this word can be explained using the International Phonetic Alphabet (IPA). The first syllable, "di", is pronounced as "dɪ", the second syllable "zo" is pronounced as "zoʊ", and the third syllable "cil" is pronounced as "sɪl". The fourth syllable "pine" is pronounced as "paɪn", followed by "ma" pronounced as "meɪ", and "leate" pronounced as "leɪt". Overall, the correct pronunciation for this word is "dɪzoʊsɪlpaɪnmeɪleɪt".

DIZOCILPINE MALEATE Meaning and Definition

1. Dizocilpine Maleate is a synthetic compound that belongs to the class of drugs known as non-competitive NMDA receptor antagonists. It is commonly used as a research tool in the field of neuroscience to study the function and role of NMDA receptors in the brain.

   NMDA receptors are a specific type of glutamate receptor found throughout the central nervous system, predominantly in the hippocampus and cerebral cortex. These receptors play a crucial role in the regulation of synaptic plasticity, learning, and memory formation. Dizocilpine Maleate acts by binding to and blocking the NMDA receptor, preventing the flow of calcium ions into the neuron and inhibiting the activity of the receptor.

   As a research tool, Dizocilpine Maleate has been used to investigate the involvement of NMDA receptors in various neurological and psychiatric disorders, including schizophrenia, depression, and addiction. By selectively blocking NMDA receptors, researchers can examine the impact on synaptic transmission, neuronal excitability, and synaptic plasticity, providing insights into the underlying mechanisms of these conditions.

   It is worth noting that Dizocilpine Maleate is not approved for clinical use in humans due to its potent and undesirable side effects, including memory impairment, psychosis, and neurotoxicity. However, its use in animal studies has provided valuable insights into the physiological and pathological functions of NMDA receptors in the brain.

Common Misspellings for DIZOCILPINE MALEATE

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Etymology of DIZOCILPINE MALEATE

The word "Dizocilpine Maleate" is not derived from classical etymology or language. It is a scientific or chemical name used to describe a compound.

"Dizocilpine" is the generic name for a drug commonly known as MK-801, which is a non-competitive antagonist of the N-Methyl-D-Aspartate (NMDA) receptor. The name is not etymologically derived but rather an invented term used to describe this specific compound.

"Maleate" is a chemical term that refers to the maleic acid salt of a compound. It is added to "Dizocilpine" in this case to create a salt form of the compound, making it easier to handle and administer. Once again, "Maleate" is not derived from classical etymology, but is a term commonly used in chemical nomenclature.