DIGOXIGENIN Meaning and
Definition
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Digoxigenin is a small molecule derived from the cardiac glycoside digitoxin, which is derived from the foxglove plant (Digitalis purpurea). It is widely used in molecular biology techniques and research as a marker for the detection of nucleic acid sequences.
In particular, digoxigenin is used as a labeling molecule to detect and visualize specific DNA or RNA sequences in various molecular biology applications such as in situ hybridization, Southern and Northern blotting, and quantitative polymerase chain reaction (qPCR). It can be linked to nucleotides through various chemical reactions, such as enzymatic or chemical labeling, to generate digoxigenin-labeled probes or primers.
The advantage of using digoxigenin as a label is its high sensitivity and specificity to detect target DNA or RNA sequences. Upon hybridization with the complementary DNA or RNA targets, digoxigenin-labeled probes can be detected using different detection methods, such as enzyme-linked immunosorbent assays (ELISA) or immunohistochemistry, with the help of specific antibodies against digoxigenin.
Digoxigenin offers a versatile and reliable tool for nucleic acid detection and localization, enabling researchers to study gene expression patterns, identify specific nucleic acid sequences, and perform detailed analyses of nucleic acid molecules. Its wide range of applications and robustness make digoxigenin a valuable reagent in molecular biology research and diagnostics.
Common Misspellings for DIGOXIGENIN
- sigoxigenin
- xigoxigenin
- cigoxigenin
- figoxigenin
- rigoxigenin
- eigoxigenin
- dugoxigenin
- djgoxigenin
- dkgoxigenin
- dogoxigenin
- d9goxigenin
- d8goxigenin
- difoxigenin
- divoxigenin
- diboxigenin
- dihoxigenin
- diyoxigenin
- ditoxigenin
- digixigenin
- digkxigenin
Etymology of DIGOXIGENIN
The word "Digoxigenin" has its etymology rooted in the names of two separate entities: "digoxin" and "genin".
1. "Digoxin": This term refers to a cardiac glycoside, extracted from the plant Digitalis purpurea (commonly known as foxglove). It has been used for centuries to treat heart-related conditions. The word "digoxin" comes from the scientific name of foxglove, "Digitalis", which is derived from the Latin word "digitus", meaning finger. This name reflects the bell-shaped flowers of the plant that resemble the fingers of gloves.
2. "Genin": This term is used in organic chemistry to denote a chemical substance derived from a larger parent molecule through the process of hydrolysis.
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