DEOXYURIDINE PHOSPHATES Meaning and
Definition
-
Deoxyuridine phosphates are a group of nucleotide derivatives that play a critical role in DNA synthesis and repair processes within living organisms. Specifically, they are components of deoxyribonucleotide triphosphates (dNTPs), which are building blocks for the synthesis of new DNA strands during replication.
Deoxyuridine phosphates are composed of a deoxyribose sugar moiety, a phosphate group, and the nucleobase uracil. Unlike ribonucleotide triphosphates (rNTPs), which contain uracil as a nucleobase in RNA molecules, DNA molecules naturally contain thymine instead. Deoxyuridine phosphates are therefore not normally found in cellular DNA, but their presence can be indicative of DNA damage or the incorporation of foreign DNA.
In normal cellular processes, an enzyme called uracil DNA glycosylase recognizes and removes any uracil nucleotides that have been mistakenly incorporated into the DNA during replication or have arisen due to spontaneous deamination of cytosine. Uracil DNA glycosylase specifically cleaves the glycosidic bond between the uracil base and the deoxyribose sugar, leaving behind an abasic site known as uracil DNA glycosylase-sensitive site.
Overall, the presence or absence of deoxyuridine phosphates within a DNA molecule can have implications for proper DNA replication, the prevention of genomic instability, and the accurate transmission of genetic information across cell generations.
Common Misspellings for DEOXYURIDINE PHOSPHATES
- seoxyuridine phosphates
- xeoxyuridine phosphates
- ceoxyuridine phosphates
- feoxyuridine phosphates
- reoxyuridine phosphates
- eeoxyuridine phosphates
- dwoxyuridine phosphates
- dsoxyuridine phosphates
- ddoxyuridine phosphates
- droxyuridine phosphates
- d4oxyuridine phosphates
- d3oxyuridine phosphates
- deixyuridine phosphates
- dekxyuridine phosphates
- delxyuridine phosphates
- depxyuridine phosphates
- de0xyuridine phosphates
- de9xyuridine phosphates
- deozyuridine phosphates
- deocyuridine phosphates
Etymology of DEOXYURIDINE PHOSPHATES
The word "deoxyuridine" is derived from the combination of three components: "deoxy-", "uridine", and "-ine".
1. "Deoxy-" is a prefix meaning "without oxygen". It is derived from the Greek word "de-" meaning "away from" or "off" and the Latin word "oxy", meaning "sharp" or "acid". In the context of "deoxyuridine", it signifies that the molecule lacks an oxygen atom compared to its parent compound, uridine.
2. "Uridine" is a nucleoside, which is a combination of the nucleobase called uracil and the sugar ribose. "Uracil" comes from the Latin word "urina", meaning "urine" because uracil was first isolated from urine.
3. "-ine" is a suffix often used to denote a compound's classification as a nitrogenous base.
Infographic
Add the infographic to your website:
