DEOXYHEMOGLOBIN S Meaning and
Definition
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Deoxyhemoglobin S refers to a specific variant of deoxyhemoglobin, which is the reduced form of hemoglobin found in the blood. Hemoglobin is a protein found in red blood cells that carries oxygen from the lungs to tissues throughout the body. Deoxyhemoglobin S, also known as sickle hemoglobin or HbS, is characterized by a structural abnormality in the beta-globin chain of the hemoglobin molecule.
The abnormality in deoxyhemoglobin S arises from a single amino acid substitution in the beta-globin chain, where valine replaces glutamic acid at the sixth position. This alteration causes the hemoglobin molecules to polymerize and form long, stiff fibers when oxygen levels are low. These fibers distort the shape of the red blood cells, causing them to become rigid and take on a crescent or sickle shape. This abnormal shape can lead to a variety of health problems.
Individuals with deoxyhemoglobin S are said to have sickle cell disease, a hereditary disorder that can result in chronic anemia, pain crises, and damage to various organs. The altered red blood cells have a decreased oxygen-carrying capacity and are more prone to clumping together, leading to blockages in blood vessels.
In summary, deoxyhemoglobin S refers to the abnormal form of reduced hemoglobin found in individuals with sickle cell disease, characterized by a genetic mutation that alters the structure of the hemoglobin molecule and influences its ability to carry oxygen efficiently.
Common Misspellings for DEOXYHEMOGLOBIN S
- seoxyhemoglobin s
- xeoxyhemoglobin s
- ceoxyhemoglobin s
- feoxyhemoglobin s
- reoxyhemoglobin s
- eeoxyhemoglobin s
- dwoxyhemoglobin s
- dsoxyhemoglobin s
- ddoxyhemoglobin s
- droxyhemoglobin s
- d4oxyhemoglobin s
- d3oxyhemoglobin s
- deixyhemoglobin s
- dekxyhemoglobin s
- delxyhemoglobin s
- depxyhemoglobin s
- de0xyhemoglobin s
- de9xyhemoglobin s
- deozyhemoglobin s
- deocyhemoglobin s
Etymology of DEOXYHEMOGLOBIN S
The word "deoxyhemoglobin S" is a technical term used in the field of biochemistry and genetics. It combines two main components: "deoxyhemoglobin" and "S".
1. Deoxyhemoglobin: The term "deoxyhemoglobin" is derived from Greek and Latin roots. The prefix "deoxy-" comes from the Greek word "deuteros" meaning "second", "missing", or "lacking". "Hemoglobin" comes from the Latin words "hema" meaning "blood" and "globus" meaning "rounded mass" or "ball". Therefore, "deoxyhemoglobin" refers to a form of hemoglobin that is lacking or missing oxygen. It is the reduced form of hemoglobin in which oxygen has been released.
2. S: The letter "S" in "deoxyhemoglobin S" stands for "substitution".
