DELTA GLOBIN Meaning and
Definition
-
Delta globin is a type of protein found in humans that forms part of the hemoglobin molecule. Hemoglobin is responsible for transporting oxygen in the bloodstream, ensuring its delivery to various tissues and organs throughout the body. Delta globin is one of the two types of globin chains that make up the hemoglobin molecule, the other being alpha globin.
The delta globin chain consists of 146 amino acids and is encoded by the HBD gene located on chromosome 11. It is primarily produced during the early stages of human development, specifically in the yolk sac and fetal liver. However, the production of delta globin decreases significantly after birth, and it becomes virtually absent in adult hemoglobin.
While delta globin is not a major component of adult hemoglobin, it plays a crucial role during fetal development. It pairs with alpha globin to form the fetal hemoglobin (HbF) molecule. Fetal hemoglobin exhibits a greater affinity for oxygen compared to adult hemoglobin, which allows for efficient oxygen transfer from the mother's bloodstream to the developing fetus.
Variations in the delta globin chain can lead to certain genetic conditions, such as delta-thalassemia. In delta-thalassemia, there is a deficiency or absence of delta globin production, resulting in abnormal hemoglobin formation. This can cause anemia and other health complications.
In summary, delta globin is a type of protein that forms part of the hemoglobin molecule and is primarily produced during fetal development. It plays a key role in fetal hemoglobin formation and is encoded by the HBD gene.
Common Misspellings for DELTA GLOBIN
- selta globin
- xelta globin
- celta globin
- felta globin
- relta globin
- eelta globin
- dwlta globin
- dslta globin
- ddlta globin
- drlta globin
- d4lta globin
- d3lta globin
- dekta globin
- depta globin
- deota globin
- delra globin
- delfa globin
- delga globin
- delya globin
- del6a globin
Etymology of DELTA GLOBIN
The word "delta" in "delta globin" originates from the Greek letter "Δ" (delta), which also represents the fourth letter in the Greek alphabet. In genetics and biochemistry, the term "delta" is commonly used to indicate a specific variant or isoform of a protein or gene. In this case, "delta globin" refers to a particular type of globin protein found in hemoglobin. The term "globin" stems from the Latin word "globus", meaning a round mass or sphere, as globin proteins form spherical structures within red blood cells.
Infographic
Add the infographic to your website:
