DELETION MUTATION Meaning and
Definition
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A deletion mutation is a type of genetic mutation that involves the removal or loss of a nucleotide or a sequence of nucleotides from the DNA molecule. Nucleotides are the building blocks of DNA and consist of a phosphate group, a sugar molecule (deoxyribose), and a nitrogenous base (adenine, thymine, cytosine, or guanine). A deletion mutation occurs when one or more nucleotides are missing from the DNA sequence, leading to a change in the genetic code.
Deletion mutations can occur in different regions of the DNA, such as within coding regions (exons) or non-coding regions (introns). Depending on the specific location and size of the deletion, they can have varying impacts on the resulting protein or RNA molecule that is transcribed and translated from the mutated DNA.
Deletion mutations can lead to a range of genetic disorders and conditions, as they can disrupt the normal functioning of genes. Larger deletions can result in a loss of genetic material, which can cause serious health problems or even be lethal. In other cases, smaller deletions within a gene can alter the reading frame, leading to a different sequence of amino acids being produced and affecting the structure and function of the resulting protein.
Deletion mutations can occur spontaneously during DNA replication, or they can be induced by external factors such as radiation, certain chemicals, or viruses. They are one of several types of mutations that can contribute to genetic diversity and the evolution of species.
Common Misspellings for DELETION MUTATION
- seletion mutation
- xeletion mutation
- celetion mutation
- feletion mutation
- reletion mutation
- eeletion mutation
- dwletion mutation
- dsletion mutation
- ddletion mutation
- drletion mutation
- d4letion mutation
- d3letion mutation
- deketion mutation
- depetion mutation
- deoetion mutation
- delwtion mutation
- delstion mutation
- deldtion mutation
- delrtion mutation
- del4tion mutation
Etymology of DELETION MUTATION
The term "deletion mutation" is formed by combining the words "deletion" and "mutation".
The word "deletion" is derived from the Latin verb "delere", which means "to destroy" or "to erase". In genetics, a deletion refers to the loss or removal of a segment of DNA from a chromosome. When a base or a sequence of bases is deleted from the DNA sequence, it can lead to a change in the genetic code and potentially affect protein synthesis, resulting in alterations or abnormalities.
The word "mutation" comes from the Latin noun "mutatio", meaning "a changing" or "a mutation". In genetics, a mutation refers to any change in the DNA sequence, such as deletions, insertions, or substitutions. Mutations can occur naturally or be induced by various factors, and they play a crucial role in genetic diversity, evolution, and the development of genetic disorders.
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