Defibrinate is spelled dɪˈfɪbrɪneɪt. The word is derived from the noun fibrin, which refers to a protein that is involved in the clotting of blood. The prefix "de-" means "to remove", indicating the removal of fibrin. The suffix "-ate" means "to make or become", indicating that the word refers to the process of removing fibrin. Defibrination is a medical procedure in which fibrin is removed from blood or other fluids. The spelling of defibrinate reflects how the word is pronounced.
Defibrinate is a verb that refers to the process of removing or extracting fibrin from a substance, usually blood or blood plasma. Fibrin is a fibrous protein that is part of the clotting mechanism in blood, responsible for coagulation and forming clots to stop bleeding.
The act of defibrination involves eliminating or destroying fibrin strands or clots within a liquid, such as blood, in order to prevent or reverse coagulation and restore flowability. This process is often carried out for medical, research, or industrial purposes. In medical settings, defibrination may be performed to prepare blood or plasma for transfusion by removing fibrin clots that could potentially cause blockages or other adverse reactions in the recipient's body.
Defibrination can be achieved through various methods, such as chemical agents or physical techniques, including mechanical agitation or filtration. Certain enzymes, such as fibrinolysin, can also be utilized to break down fibrin in a controlled manner.
By defibrinating blood or plasma, the concentration of fibrinogen (a precursor protein to fibrin) is notably reduced, resulting in decreased clotting potential. This allows for smoother flow, separation of components, or further processing of the liquid for various applications.
Overall, the term defibrinate is mainly associated with the removal of fibrin to promote fluidity and prevent coagulation in substances, notably blood or blood plasma.
The word defibrinate is derived from the combining form de- meaning from or undo and the word fibrin which refers to a protein involved in blood clotting. Therefore, defibrinate literally means to remove fibrin or to undo the process of fibrin formation.