DEFEROXAMINE Meaning and
Definition
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Deferoxamine, also known as desferrioxamine B or DFO, is a pharmaceutical drug primarily used as a chelating agent in the treatment of iron overload. It is classified as an iron-chelating agent due to its ability to bind to excess iron in the body and facilitate its excretion from the system.
The primary therapeutic application of deferoxamine is in the management of chronic iron overload conditions, such as transfusion-dependent thalassemia and certain types of hemochromatosis. Iron overload can occur as a result of multiple blood transfusions or diseases that interfere with normal iron metabolism, leading to complications such as organ damage and increased susceptibility to infections. Deferoxamine helps to counteract these effects by binding to the excess iron and promoting its elimination through urine and feces.
Deferoxamine is administered either through intravenous infusion or subcutaneous injection. Its mode of action involves the formation of a stable complex with iron, thereby preventing the metal from participating in oxidative reactions that could generate damaging free radicals. By removing excess iron, deferoxamine can prevent iron-induced tissue damage and reduce the risk of associated complications.
Adverse effects of deferoxamine can include allergic reactions, gastrointestinal disturbances, and rare cases of visual and auditory impairment. Continuous monitoring of patients receiving deferoxamine therapy is essential to ensure appropriate dosing and to promptly identify and manage any potential side effects.
Common Misspellings for DEFEROXAMINE
- seferoxamine
- xeferoxamine
- ceferoxamine
- feferoxamine
- referoxamine
- eeferoxamine
- dwferoxamine
- dsferoxamine
- ddferoxamine
- drferoxamine
- d4feroxamine
- d3feroxamine
- dederoxamine
- deceroxamine
- deveroxamine
- degeroxamine
- deteroxamine
- dereroxamine
- defwroxamine
- defsroxamine
Etymology of DEFEROXAMINE
The word "Deferoxamine" is derived from a combination of three components: "de-", "ferox", and "-amine".
1. "De-" is a prefix of Latin origin, meaning "opposite" or "undoing". In this context, it suggests the reversal or removal of something.
2. "Ferox" is a Latin word meaning "ferocious" or "wild". In this case, it refers to the iron deposits or overload in the body.
3. "-amine" is a suffix indicating the presence of an amine group, which refers to a type of organic compound containing a basic nitrogen atom.
When combined, the three components form "Deferoxamine", a drug primarily used for the chelation (reversal) of iron overload in the body.
Similar spelling word for DEFEROXAMINE
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