The word "dansyl chloride" is spelled with nine letters in English. When broken down into phonetic transcription, the word is pronounced as /ˈdænsəl ˈklɔːraɪd/ using the International Phonetic Alphabet. The first syllable "dan" is pronounced with a short "a" sound, followed by the "syl" syllable with an "i" sound. The "chloride" is pronounced as "klaw-raid" with the "or" sound pronounced as "aw." This chemical compound is commonly used in organic chemistry for lab research purposes.
Dansyl chloride is a chemical compound widely used in biochemical research and analytical chemistry. It is an organic compound belonging to the class of aromatic halides, and it contains a dansyl (1-dimethylaminonaphthalene-5-sulfonyl) group attached to a chlorine atom. The compound is also known by other names, such as 5-dimethylaminonaphthalene-1-sulfonyl chloride or DNS chloride.
Dansyl chloride is primarily used as a reagent for labeling amino acids, proteins, and other biomolecules. It reacts specifically with amino groups, forming stable sulfonamide bonds. This allows for the fluorescent labeling and identification of peptides and proteins in biological samples, facilitating their detection and characterization. The dansyl group imparts fluorescence properties to the labeled molecules, enabling their visualization and tracking during experiments.
Additionally, dansyl chloride finds application in the determination of amino acids and peptides using chromatographic techniques. The compound can also be employed for the detection of carbonyl compounds or as a derivatization agent in gas chromatography.
Due to its reactivity and stability, dansyl chloride is widely utilized as a versatile tool in molecular biology, biochemistry, and analytical chemistry. Its ability to form stable and fluorescent derivatives makes it an invaluable reagent for various methods and assays used in these scientific fields.
The word "dansyl chloride" is derived from the combination of two separate components: "dansyl" and "chloride".
The term "dansyl" refers to a specific chemical compound called dansyl group, which is a fluorescent dye molecule. The dye was first synthesized by the German chemist Hugo H. Heidelberger in 1950. He named it after the French chemist Gabriel Bertrand Dansyl.
On the other hand, "chloride" is a chemical term that refers to the negatively charged ion of chlorine (Cl-). Chloride ions are commonly found in various chemical compounds and play important roles in chemical reactions and biological processes.
When these two terms are combined, "dansyl chloride" refers to a specific compound where the chloride ion is attached to the dansyl group.