CXC CHEMOKINES Meaning and
Definition
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CXC chemokines refer to a subfamily of chemokines, which are small signaling proteins involved in the immune response and inflammation. Chemokines are secreted by various cells, including immune cells, and function by attracting and activating other cells towards the site of inflammation or infection. The CXC chemokines are characterized by the presence of two cysteine molecules separated by one amino acid in their amino acid sequence.
These chemokines play a crucial role in guiding immune cells, mainly neutrophils, to the site of injury or infection. They accomplish this by binding to specific receptors on the surface of immune cells, initiating a signaling cascade that results in cell migration.
CXC chemokines are involved in various physiological and pathological processes, such as inflammation, wound healing, and immune cell trafficking. Their dysregulation has been associated with several diseases, including cancer, autoimmune disorders, and inflammatory conditions.
Examples of CXC chemokines include CXCL1, CXCL2 (also known as GRO-alpha and GRO-beta, respectively), and CXCL8 (also known as interleukin-8 or IL-8). Each CXC chemokine exhibits a unique profile of chemotactic activity, receptor specificity, and mode of regulation.
In summary, CXC chemokines are a subset of chemokines that play a crucial role in immune response regulation, primarily by attracting and activating neutrophils and other immune cells. Their dysregulation can contribute to various diseases, making them important targets for therapeutic interventions.
Common Misspellings for CXC CHEMOKINES
- xxc chemokines
- vxc chemokines
- fxc chemokines
- dxc chemokines
- czc chemokines
- csc chemokines
- cxx chemokines
- cxv chemokines
- cxf chemokines
- cxd chemokines
- cxc xhemokines
- cxc vhemokines
- cxc fhemokines
- cxc dhemokines
- cxc cgemokines
- cxc cbemokines
- cxc cnemokines
- cxc cjemokines
- cxc cuemokines
- cxc cyemokines
Etymology of CXC CHEMOKINES
The etymology of the term "CXC chemokines" can be broken down as follows:
1. CXC: The term "CXC" refers to a specific arrangement of two cysteine amino acids separated by another amino acid (usually represented as "X"). This sequence is characteristic of a family of chemokines, which are small proteins that play a crucial role in immune responses.
2. Chemokines: The term "chemokines" itself comes from the combination of two words: "chemo" meaning chemical and "kines" meaning movement. Chemokines are signaling molecules that help regulate the movement and migration of immune cells to specific areas of the body.
Therefore, "CXC chemokines" specifically refers to a subclass of chemokines that have the CXC arrangement of cysteine amino acids in their structure.
