CRYSTALLIN Meaning and
Definition
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Crystallin refers to a group of proteins that are predominantly found in the lens of the eye. These proteins play a crucial role in maintaining the transparency and structural integrity of the lens, thereby ensuring proper vision. Crystallins represent one of the major components of the lens and are responsible for its unique refractive properties.
The term "crystallin" is derived from the crystalline nature of these proteins, as their three-dimensional structure resembles that of a crystal lattice. They have a high affinity for water, helping to maintain proper hydration levels within the lens. There are three major types of crystallins: α-crystallin, β-crystallin, and γ-crystallin.
α-crystallin is further categorized into two subunits: αA-crystallin and αB-crystallin. It acts as a molecular chaperone, preventing the aggregation and denaturation of other proteins in the lens. β-crystallin proteins are highly organized and are primarily responsible for the optical properties of the lens, as they contribute to its refractive index. Finally, γ-crystallins are the most abundant of the three types and help maintain the structural integrity of the lens through their contribution to its transparency.
The proper functioning and arrangement of crystallins are vital for maintaining clear vision and preventing the development of cataracts. Any dysfunction or abnormality in these proteins can lead to the development of lens opacities, which can impair vision.
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1. A globulin in the crystalline lens of the eye. 2. A solution of pyroxylin 1, in methyl alcohol 4, and amyl acetate 15; similar in properties and use to collodion.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for CRYSTALLIN
- cruystalline
- crystalline
- crystallyne
- xrystallin
- vrystallin
- frystallin
- drystallin
- ceystallin
- cdystallin
- cfystallin
- ctystallin
- c5ystallin
- c4ystallin
- crtstallin
- crgstallin
- crhstallin
- crustallin
- cr7stallin
- cr6stallin
- cryatallin
Etymology of CRYSTALLIN
The word "crystallin" comes from the noun "crystal", which originated from the Latin word "crystallus" and the Greek word "krustallos". Both of these words refer to ice and crystals. "Crystallin" is derived from "crystal" by adding the suffix "-in", which is commonly used in chemistry and biology to denote a protein. Therefore, "crystallin" refers to a protein found in the crystalline lens of the eye.
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