Cryptococcus is a genus of fungi that is commonly found in soil and bird droppings. The spelling of Cryptococcus comes from its Greek roots: kryp- meaning "hidden" or "secret", and -coccus meaning "berry-shaped". The 'p' in kryp becomes silent when combined with the 'c' in -coccus, resulting in [krip-tuh-koh-kuh s] in IPA phonetic transcription. Cryptococcus can cause serious infections in immunocompromised individuals and is responsible for cryptococcal meningitis, a potentially deadly illness.
Cryptococcus is a genus of fungi that belongs to the Basidiomycota phylum. It is characterized by its ability to produce sexual and asexual spores, and it mainly thrives in soil and organic matter such as decaying wood and bird droppings. Cryptococcus can cause opportunistic infections in humans, particularly in individuals with a weakened immune system, such as those living with HIV/AIDS or undergoing immunosuppressive therapy after organ transplantation.
The most common species within the Cryptococcus genus is Cryptococcus neoformans, which is responsible for causing cryptococcosis. This invasive fungal infection typically affects the lungs, central nervous system, and may spread to other organs, leading to life-threatening conditions such as meningitis and pneumonia. Symptoms of cryptococcosis may vary depending on the sites of infection but often include fever, cough, headache, and neurological abnormalities.
Cryptococcus neoformans is capable of evading the body's immune system by disguising itself with an external polysaccharide capsule. This capsule provides protection against host defenses and allows the fungus to survive and proliferate within the human body. Diagnosis of Cryptococcus infection usually involves laboratory tests to identify the organism in biological specimens, such as cerebrospinal fluid or tissue samples.
Treatment typically involves antifungal medications, such as amphotericin B and fluconazole, administered over an extended period. In severe cases, surgical intervention may be necessary to remove fungal masses. Despite advances in treatment, cryptococcosis remains a significant concern for immunocompromised individuals, emphasizing the importance of prevention strategies and early detection in high-risk populations.
A genus of fungi reproducing by budding only, no spores being in evidence; Blastomyces, Zymonema. C. dermatitis, the cause of one form of blastomycosis.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word "Cryptococcus" has a Greek origin. It comes from the combination of two Greek words: "kryptos", meaning "hidden" or "concealed", and "kokkus", meaning "berry" or "grain". The term "Crypto"coccus refers to the round or oval shape of the yeast-like fungal cells that are typically encapsulated or surrounded by a protective gelatinous layer, making them appear concealed or hidden.